Emerging utility of once-weekly exenatide in patients with type 2 diabetes

Aditya Goud, Jixin Zhong, Sanjay RajagopalanDivision of Cardiovascular Medicine, Department of Medicine, University of Maryland, Baltimore, MD, USAAbstract: Type 2 diabetes mellitus (T2DM) is a major risk factor for the development of cardiovascular disease (CVD). Due to the ever increasing incidenc...

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Autores principales: Goud A, Zhong J, Rajagopalan S
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Lenguaje:EN
Publicado: Dove Medical Press 2015
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Acceso en línea:https://doaj.org/article/90df0cef555e4836a09f0443ce732411
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spelling oai:doaj.org-article:90df0cef555e4836a09f0443ce7324112021-12-02T06:25:56ZEmerging utility of once-weekly exenatide in patients with type 2 diabetes1178-7007https://doaj.org/article/90df0cef555e4836a09f0443ce7324112015-10-01T00:00:00Zhttps://www.dovepress.com/emerging-utility-of-once-weekly-exenatide-in-patients-with-type-2-diab-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Aditya Goud, Jixin Zhong, Sanjay RajagopalanDivision of Cardiovascular Medicine, Department of Medicine, University of Maryland, Baltimore, MD, USAAbstract: Type 2 diabetes mellitus (T2DM) is a major risk factor for the development of cardiovascular disease (CVD). Due to the ever increasing incidence of both T2DM and CVD and coexistence of these disorders, numerous agents have been developed over the years to target complications. We focus on the efficacy and safety perspective of a long-acting formulation of the glucagon-like peptide-1 analog exenatide. Our review focuses on the various landmark trials, efficacy, safety profile, and patient perspectives of weekly exenatide that delineates its current and future role in the treatment of patients with T2DM and CVD.Keywords: incretin, glucagon-like peptide, hyperglycemia, glucose loweringGoud AZhong JRajagopalan SDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2015, Iss default, Pp 505-512 (2015)
institution DOAJ
collection DOAJ
language EN
topic Specialties of internal medicine
RC581-951
spellingShingle Specialties of internal medicine
RC581-951
Goud A
Zhong J
Rajagopalan S
Emerging utility of once-weekly exenatide in patients with type 2 diabetes
description Aditya Goud, Jixin Zhong, Sanjay RajagopalanDivision of Cardiovascular Medicine, Department of Medicine, University of Maryland, Baltimore, MD, USAAbstract: Type 2 diabetes mellitus (T2DM) is a major risk factor for the development of cardiovascular disease (CVD). Due to the ever increasing incidence of both T2DM and CVD and coexistence of these disorders, numerous agents have been developed over the years to target complications. We focus on the efficacy and safety perspective of a long-acting formulation of the glucagon-like peptide-1 analog exenatide. Our review focuses on the various landmark trials, efficacy, safety profile, and patient perspectives of weekly exenatide that delineates its current and future role in the treatment of patients with T2DM and CVD.Keywords: incretin, glucagon-like peptide, hyperglycemia, glucose lowering
format article
author Goud A
Zhong J
Rajagopalan S
author_facet Goud A
Zhong J
Rajagopalan S
author_sort Goud A
title Emerging utility of once-weekly exenatide in patients with type 2 diabetes
title_short Emerging utility of once-weekly exenatide in patients with type 2 diabetes
title_full Emerging utility of once-weekly exenatide in patients with type 2 diabetes
title_fullStr Emerging utility of once-weekly exenatide in patients with type 2 diabetes
title_full_unstemmed Emerging utility of once-weekly exenatide in patients with type 2 diabetes
title_sort emerging utility of once-weekly exenatide in patients with type 2 diabetes
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/90df0cef555e4836a09f0443ce732411
work_keys_str_mv AT gouda emergingutilityofonceweeklyexenatideinpatientswithtype2diabetes
AT zhongj emergingutilityofonceweeklyexenatideinpatientswithtype2diabetes
AT rajagopalans emergingutilityofonceweeklyexenatideinpatientswithtype2diabetes
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