Enhanced nanochannel translocation and localization of genomic DNA molecules using three-dimensional nanofunnels
Forcing a DNA molecule into a nanoscale channel requires overcoming the free energy barrier associated with confinement. Here, the authors show that DNA injected through a funnel-shaped entrance more efficiently enters the nanochannel, thanks to facilitating forces generated by the nanofunnel geomet...
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Autores principales: | Jinsheng Zhou, Yanqian Wang, Laurent D. Menard, Sergey Panyukov, Michael Rubinstein, J. Michael Ramsey |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/90e75e0ea21644aba7c371d9aa9dd827 |
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