Enhanced nanochannel translocation and localization of genomic DNA molecules using three-dimensional nanofunnels

Forcing a DNA molecule into a nanoscale channel requires overcoming the free energy barrier associated with confinement. Here, the authors show that DNA injected through a funnel-shaped entrance more efficiently enters the nanochannel, thanks to facilitating forces generated by the nanofunnel geomet...

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Bibliographic Details
Main Authors: Jinsheng Zhou, Yanqian Wang, Laurent D. Menard, Sergey Panyukov, Michael Rubinstein, J. Michael Ramsey
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/90e75e0ea21644aba7c371d9aa9dd827
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