Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization

Brain function alterations in schizophrenia and other psychotic disorders remain poorly understood. Here, the authors discover that increased neural connectivity in the cerebello-thalamo-cortical circuitry predicts psychosis in those at high risk, and is present in people with schizophrenia.

Guardado en:

Detalles Bibliográficos
Autores principales:	Hengyi Cao, Oliver Y. Chén, Yoonho Chung, Jennifer K. Forsyth, Sarah C. McEwen, Dylan G. Gee, Carrie E. Bearden, Jean Addington, Bradley Goodyear, Kristin S. Cadenhead, Heline Mirzakhanian, Barbara A. Cornblatt, Ricardo E. Carrión, Daniel H. Mathalon, Thomas H. McGlashan, Diana O. Perkins, Aysenil Belger, Larry J. Seidman, Heidi Thermenos, Ming T. Tsuang, Theo G. M. van Erp, Elaine F. Walker, Stephan Hamann, Alan Anticevic, Scott W. Woods, Tyrone D. Cannon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/90e889c2e50f47319e444c8a9c82d126
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:90e889c2e50f47319e444c8a9c82d126
record_format	dspace
spelling	oai:doaj.org-article:90e889c2e50f47319e444c8a9c82d1262021-12-02T17:31:46ZCerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization10.1038/s41467-018-06350-72041-1723https://doaj.org/article/90e889c2e50f47319e444c8a9c82d1262018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06350-7https://doaj.org/toc/2041-1723Brain function alterations in schizophrenia and other psychotic disorders remain poorly understood. Here, the authors discover that increased neural connectivity in the cerebello-thalamo-cortical circuitry predicts psychosis in those at high risk, and is present in people with schizophrenia.Hengyi CaoOliver Y. ChénYoonho ChungJennifer K. ForsythSarah C. McEwenDylan G. GeeCarrie E. BeardenJean AddingtonBradley GoodyearKristin S. CadenheadHeline MirzakhanianBarbara A. CornblattRicardo E. CarriónDaniel H. MathalonThomas H. McGlashanDiana O. PerkinsAysenil BelgerLarry J. SeidmanHeidi ThermenosMing T. TsuangTheo G. M. van ErpElaine F. WalkerStephan HamannAlan AnticevicScott W. WoodsTyrone D. CannonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hengyi Cao Oliver Y. Chén Yoonho Chung Jennifer K. Forsyth Sarah C. McEwen Dylan G. Gee Carrie E. Bearden Jean Addington Bradley Goodyear Kristin S. Cadenhead Heline Mirzakhanian Barbara A. Cornblatt Ricardo E. Carrión Daniel H. Mathalon Thomas H. McGlashan Diana O. Perkins Aysenil Belger Larry J. Seidman Heidi Thermenos Ming T. Tsuang Theo G. M. van Erp Elaine F. Walker Stephan Hamann Alan Anticevic Scott W. Woods Tyrone D. Cannon Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization
description	Brain function alterations in schizophrenia and other psychotic disorders remain poorly understood. Here, the authors discover that increased neural connectivity in the cerebello-thalamo-cortical circuitry predicts psychosis in those at high risk, and is present in people with schizophrenia.
format	article
author	Hengyi Cao Oliver Y. Chén Yoonho Chung Jennifer K. Forsyth Sarah C. McEwen Dylan G. Gee Carrie E. Bearden Jean Addington Bradley Goodyear Kristin S. Cadenhead Heline Mirzakhanian Barbara A. Cornblatt Ricardo E. Carrión Daniel H. Mathalon Thomas H. McGlashan Diana O. Perkins Aysenil Belger Larry J. Seidman Heidi Thermenos Ming T. Tsuang Theo G. M. van Erp Elaine F. Walker Stephan Hamann Alan Anticevic Scott W. Woods Tyrone D. Cannon
author_facet	Hengyi Cao Oliver Y. Chén Yoonho Chung Jennifer K. Forsyth Sarah C. McEwen Dylan G. Gee Carrie E. Bearden Jean Addington Bradley Goodyear Kristin S. Cadenhead Heline Mirzakhanian Barbara A. Cornblatt Ricardo E. Carrión Daniel H. Mathalon Thomas H. McGlashan Diana O. Perkins Aysenil Belger Larry J. Seidman Heidi Thermenos Ming T. Tsuang Theo G. M. van Erp Elaine F. Walker Stephan Hamann Alan Anticevic Scott W. Woods Tyrone D. Cannon
author_sort	Hengyi Cao
title	Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization
title_short	Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization
title_full	Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization
title_fullStr	Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization
title_full_unstemmed	Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization
title_sort	cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/90e889c2e50f47319e444c8a9c82d126
work_keys_str_mv	AT hengyicao cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT oliverychen cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT yoonhochung cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT jenniferkforsyth cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT sarahcmcewen cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT dylanggee cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT carrieebearden cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT jeanaddington cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT bradleygoodyear cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT kristinscadenhead cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT helinemirzakhanian cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT barbaraacornblatt cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT ricardoecarrion cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT danielhmathalon cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT thomashmcglashan cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT dianaoperkins cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT aysenilbelger cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT larryjseidman cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT heidithermenos cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT mingttsuang cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT theogmvanerp cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT elainefwalker cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT stephanhamann cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT alananticevic cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT scottwwoods cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization AT tyronedcannon cerebellothalamocorticalhyperconnectivityasastateindependentfunctionalneuralsignatureforpsychosispredictionandcharacterization
_version_	1718380505392480256

Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization

Ejemplares similares