Mathematical framework for place coding in the auditory system.

In the auditory system, tonotopy is postulated to be the substrate for a place code, where sound frequency is encoded by the location of the neurons that fire during the stimulus. Though conceptually simple, the computations that allow for the representation of intensity and complex sounds are poorl...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Alex D Reyes
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/90f15faace2b48958af6992d5ec7fb25
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:90f15faace2b48958af6992d5ec7fb25
record_format	dspace
spelling	oai:doaj.org-article:90f15faace2b48958af6992d5ec7fb252021-12-02T19:58:09ZMathematical framework for place coding in the auditory system.1553-734X1553-735810.1371/journal.pcbi.1009251https://doaj.org/article/90f15faace2b48958af6992d5ec7fb252021-08-01T00:00:00Zhttps://doi.org/10.1371/journal.pcbi.1009251https://doaj.org/toc/1553-734Xhttps://doaj.org/toc/1553-7358In the auditory system, tonotopy is postulated to be the substrate for a place code, where sound frequency is encoded by the location of the neurons that fire during the stimulus. Though conceptually simple, the computations that allow for the representation of intensity and complex sounds are poorly understood. Here, a mathematical framework is developed in order to define clearly the conditions that support a place code. To accommodate both frequency and intensity information, the neural network is described as a space with elements that represent individual neurons and clusters of neurons. A mapping is then constructed from acoustic space to neural space so that frequency and intensity are encoded, respectively, by the location and size of the clusters. Algebraic operations -addition and multiplication- are derived to elucidate the rules for representing, assembling, and modulating multi-frequency sound in networks. The resulting outcomes of these operations are consistent with network simulations as well as with electrophysiological and psychophysical data. The analyses show how both frequency and intensity can be encoded with a purely place code, without the need for rate or temporal coding schemes. The algebraic operations are used to describe loudness summation and suggest a mechanism for the critical band. The mathematical approach complements experimental and computational approaches and provides a foundation for interpreting data and constructing models.Alex D ReyesPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Computational Biology, Vol 17, Iss 8, p e1009251 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Alex D Reyes Mathematical framework for place coding in the auditory system.
description	In the auditory system, tonotopy is postulated to be the substrate for a place code, where sound frequency is encoded by the location of the neurons that fire during the stimulus. Though conceptually simple, the computations that allow for the representation of intensity and complex sounds are poorly understood. Here, a mathematical framework is developed in order to define clearly the conditions that support a place code. To accommodate both frequency and intensity information, the neural network is described as a space with elements that represent individual neurons and clusters of neurons. A mapping is then constructed from acoustic space to neural space so that frequency and intensity are encoded, respectively, by the location and size of the clusters. Algebraic operations -addition and multiplication- are derived to elucidate the rules for representing, assembling, and modulating multi-frequency sound in networks. The resulting outcomes of these operations are consistent with network simulations as well as with electrophysiological and psychophysical data. The analyses show how both frequency and intensity can be encoded with a purely place code, without the need for rate or temporal coding schemes. The algebraic operations are used to describe loudness summation and suggest a mechanism for the critical band. The mathematical approach complements experimental and computational approaches and provides a foundation for interpreting data and constructing models.
format	article
author	Alex D Reyes
author_facet	Alex D Reyes
author_sort	Alex D Reyes
title	Mathematical framework for place coding in the auditory system.
title_short	Mathematical framework for place coding in the auditory system.
title_full	Mathematical framework for place coding in the auditory system.
title_fullStr	Mathematical framework for place coding in the auditory system.
title_full_unstemmed	Mathematical framework for place coding in the auditory system.
title_sort	mathematical framework for place coding in the auditory system.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/90f15faace2b48958af6992d5ec7fb25
work_keys_str_mv	AT alexdreyes mathematicalframeworkforplacecodingintheauditorysystem
_version_	1718375790371930112

Mathematical framework for place coding in the auditory system.

Ejemplares similares