Adverse effects of cigarette smoking on exhaled breath carbon monoxide, blood carboxyhemoglobin, and hematological parameters amongst Sri Lankan adult tobacco smokers: A descriptive study
Introduction Tobacco smoking is the single most preventable cause of death worldwide and a major risk factor for several non-communicable diseases. Tobacco smoking has both acute and chronic effects on hematological parameters. The study aims to assess the effects of smoking intensity on exhaled bre...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
European Publishing
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/90fd6aff0a3a4601b6147a40e04da5da |
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| Sumario: | Introduction
Tobacco smoking is the single most
preventable cause of death worldwide and a major risk
factor for several non-communicable diseases. Tobacco
smoking has both acute and chronic effects on hematological
parameters. The study aims to assess the effects of smoking
intensity on exhaled breath carbon monoxide (eCO),
carboxyhemoglobin (COHb%) and hematological parameters.
Methods
Adult male daily smokers (n=360) and matched
non-smoking males (n=180) from Colombo district, Sri
Lanka, were selected. Sociodemographic data, smoking habits
and anthropometric data were recorded. An automated
Smokerlyser (Smokerlyser®, Bedfont) was used to estimate
eCO and COHb% in exhaled breath and Brinkman index was
used to quantify the level of smoking exposure. A venous
blood sample was analyzed for a full blood count. Smokers
were compared with the non-smoking group.
Results
Smokers had significantly higher values of eCO,
COHb%, Hemoglobin (Hb), Hematocrit (HCT), Mean
Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin
(MCH), Mean Corpuscular Hemoglobin Concentration
(MCHC), total White Blood Cell total count (WBC),
Lymphocyte count, Monocyte count, and Granulocyte count.
The number of cigarettes per day, duration of smoking, and
Brinkman index were positively correlated with eCO and
COHb%. MCV and MCH were positively correlated with the
number of cigarettes smoked per day, smoking duration, and
Brinkman index.
Conclusions
The severity of smoking can be quantified
by the exhaled breath CO and blood COHb% levels as
these parameters correlate with the severity of smoking.
Hematological parameters of smokers were affected with
continued long-term low-intensity smoking. |
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