A frequent PNPLA3 variant is a sex specific disease modifier in PSC patients with bile duct stenosis.

A frequent PNPLA3 variant is a sex specific disease modifier in PSC patients with bile duct stenosis.

<h4>Background aims</h4>Primary sclerosing cholangitis predominantly affects males and is an important indication for liver transplantation. The rs738409 variant (I148M) of the PNPLA3 gene is associated with alcoholic and non-alcoholic liver disease and we evaluated its impact on the dis...

Full description

Saved in:
Bibliographic Details
Main Authors: Kilian Friedrich, Christian Rupp, Johannes Roksund Hov, Niels Steinebrunner, Karl-Heinz Weiss, Adolf Stiehl, Maik Brune, Petra Kloeters Yvonne Schaefer, Peter Schemmer, Peter Sauer, Peter Schirmacher, Heiko Runz, Tom Hemming Karlsen, Wolfgang Stremmel, Daniel Nils Gotthardt
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/9102ced40ef94cce837eefe5c840c95d
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/9102ced40ef94cce837eefe5c840c95d

Similar Items