Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis

Li et al. show that dipeptidyl peptidase 4 (DPP4) promotes peritoneal fibrosis whereas the inhibition of DPP4 protects the patients from failure of peritoneal dialysis. This study provides mechanistic insights into the effects of DPP4 on peritoneal fibrosis and the translational potential of these e...

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Autores principales: Yi-Chen Li, Pei-Hsun Sung, Yao-Hsu Yang, John Y. Chiang, Hon-Kan Yip, Chih‐Chao Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/911bba4595054801a4caa71ada15a35b
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spelling oai:doaj.org-article:911bba4595054801a4caa71ada15a35b2021-12-02T13:23:49ZDipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis10.1038/s42003-021-01652-x2399-3642https://doaj.org/article/911bba4595054801a4caa71ada15a35b2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01652-xhttps://doaj.org/toc/2399-3642Li et al. show that dipeptidyl peptidase 4 (DPP4) promotes peritoneal fibrosis whereas the inhibition of DPP4 protects the patients from failure of peritoneal dialysis. This study provides mechanistic insights into the effects of DPP4 on peritoneal fibrosis and the translational potential of these effects.Yi-Chen LiPei-Hsun SungYao-Hsu YangJohn Y. ChiangHon-Kan YipChih‐Chao YangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Yi-Chen Li
Pei-Hsun Sung
Yao-Hsu Yang
John Y. Chiang
Hon-Kan Yip
Chih‐Chao Yang
Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis
description Li et al. show that dipeptidyl peptidase 4 (DPP4) promotes peritoneal fibrosis whereas the inhibition of DPP4 protects the patients from failure of peritoneal dialysis. This study provides mechanistic insights into the effects of DPP4 on peritoneal fibrosis and the translational potential of these effects.
format article
author Yi-Chen Li
Pei-Hsun Sung
Yao-Hsu Yang
John Y. Chiang
Hon-Kan Yip
Chih‐Chao Yang
author_facet Yi-Chen Li
Pei-Hsun Sung
Yao-Hsu Yang
John Y. Chiang
Hon-Kan Yip
Chih‐Chao Yang
author_sort Yi-Chen Li
title Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis
title_short Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis
title_full Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis
title_fullStr Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis
title_full_unstemmed Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis
title_sort dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/911bba4595054801a4caa71ada15a35b
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