Robust inference of kinase activity using functional networks

Robust inference of kinase activity using functional networks

Kinases drive fundamental changes in cell state, but predicting kinase activity based on substrate-level changes can be challenging. Here the authors introduce a computational framework that utilizes similarities between substrates to robustly infer kinase activity.

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Detalles Bibliográficos
Autores principales: Serhan Yılmaz, Marzieh Ayati, Daniela Schlatzer, A. Ercüment Çiçek, Mark R. Chance, Mehmet Koyutürk
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/91396e4de4ab46f3a89cbb70ee623194
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