Review of environmental factors and juvenile idiopathic arthritis

Daniel B Horton,1–3 Susan Shenoi4 1Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; 2Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; 3Department...

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Autores principales: Horton DB, Shenoi S
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Lenguaje:EN
Publicado: Dove Medical Press 2019
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spelling oai:doaj.org-article:914d2e762268427db116464a73e99c512021-12-02T03:24:41ZReview of environmental factors and juvenile idiopathic arthritis1179-156Xhttps://doaj.org/article/914d2e762268427db116464a73e99c512019-11-01T00:00:00Zhttps://www.dovepress.com/review-of-environmental-factors-and-juvenile-idiopathic-arthritis-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XDaniel B Horton,1–3 Susan Shenoi4 1Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; 2Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; 3Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA; 4Department of Pediatrics, Division of Pediatric Rheumatology, Seattle Children’s Hospital and Research Center and University of Washington, Seattle, WA, USACorrespondence: Susan ShenoiDivision of Rheumatology, Seattle Children’s Hospital, Mailstop: MA.7.110, 4800 Sand Point Way NE, Seattle, WA 98105, USATel +1 206 987 2000Fax +1 206 987 5060Email susan.shenoi@seattlechildrens.orgAbstract: Juvenile idiopathic arthritis is a common rheumatic disease that presents as chronic childhood arthritis. JIA is considered a multifactorial disease that may result from diverse genetic and environmental risk factors. A minority of the population-attributable risk of JIA is estimated to be due to familial factors. Thus, non-genetic or environmental factors likely account for a majority of the risk of developing JIA. Yet, while substantial data have linked environmental factors to the development of rheumatoid arthritis, similar evidence regarding JIA is sparse. This narrative review provides updates on recent literature about environmental factors that might influence the risk of developing JIA, including studies about potentially beneficial and harmful influences as well as factors with unclear effects.Keywords: environmental exposure, risk factors, juvenile arthritis, antibiotics, breast feeding, cesarean sectionHorton DBShenoi SDove Medical Pressarticleenvironmental exposurerisk factorsjuvenile arthritisantibioticsbreast feedingcesarean sectionDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 11, Pp 253-267 (2019)
institution DOAJ
collection DOAJ
language EN
topic environmental exposure
risk factors
juvenile arthritis
antibiotics
breast feeding
cesarean section
Diseases of the musculoskeletal system
RC925-935
spellingShingle environmental exposure
risk factors
juvenile arthritis
antibiotics
breast feeding
cesarean section
Diseases of the musculoskeletal system
RC925-935
Horton DB
Shenoi S
Review of environmental factors and juvenile idiopathic arthritis
description Daniel B Horton,1–3 Susan Shenoi4 1Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA; 2Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, USA; 3Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA; 4Department of Pediatrics, Division of Pediatric Rheumatology, Seattle Children’s Hospital and Research Center and University of Washington, Seattle, WA, USACorrespondence: Susan ShenoiDivision of Rheumatology, Seattle Children’s Hospital, Mailstop: MA.7.110, 4800 Sand Point Way NE, Seattle, WA 98105, USATel +1 206 987 2000Fax +1 206 987 5060Email susan.shenoi@seattlechildrens.orgAbstract: Juvenile idiopathic arthritis is a common rheumatic disease that presents as chronic childhood arthritis. JIA is considered a multifactorial disease that may result from diverse genetic and environmental risk factors. A minority of the population-attributable risk of JIA is estimated to be due to familial factors. Thus, non-genetic or environmental factors likely account for a majority of the risk of developing JIA. Yet, while substantial data have linked environmental factors to the development of rheumatoid arthritis, similar evidence regarding JIA is sparse. This narrative review provides updates on recent literature about environmental factors that might influence the risk of developing JIA, including studies about potentially beneficial and harmful influences as well as factors with unclear effects.Keywords: environmental exposure, risk factors, juvenile arthritis, antibiotics, breast feeding, cesarean section
format article
author Horton DB
Shenoi S
author_facet Horton DB
Shenoi S
author_sort Horton DB
title Review of environmental factors and juvenile idiopathic arthritis
title_short Review of environmental factors and juvenile idiopathic arthritis
title_full Review of environmental factors and juvenile idiopathic arthritis
title_fullStr Review of environmental factors and juvenile idiopathic arthritis
title_full_unstemmed Review of environmental factors and juvenile idiopathic arthritis
title_sort review of environmental factors and juvenile idiopathic arthritis
publisher Dove Medical Press
publishDate 2019
url https://doaj.org/article/914d2e762268427db116464a73e99c51
work_keys_str_mv AT hortondb reviewofenvironmentalfactorsandjuvenileidiopathicarthritis
AT shenois reviewofenvironmentalfactorsandjuvenileidiopathicarthritis
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