Co-transmission of acetylcholine and GABA regulates hippocampal states

Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non-synaptically in volume transmission. Here, Takács and colleagues show cholinergic terminals juxtapose GABAergic synapses anatomically and functionally, and GABA and ACh molecules are co-transmitted.

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Autores principales: Virág T. Takács, Csaba Cserép, Dániel Schlingloff, Balázs Pósfai, András Szőnyi, Katalin E. Sos, Zsuzsanna Környei, Ádám Dénes, Attila I. Gulyás, Tamás F. Freund, Gábor Nyiri
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9152c00a8484415dbce6f767cb36a338
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spelling oai:doaj.org-article:9152c00a8484415dbce6f767cb36a3382021-12-02T17:31:43ZCo-transmission of acetylcholine and GABA regulates hippocampal states10.1038/s41467-018-05136-12041-1723https://doaj.org/article/9152c00a8484415dbce6f767cb36a3382018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05136-1https://doaj.org/toc/2041-1723Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non-synaptically in volume transmission. Here, Takács and colleagues show cholinergic terminals juxtapose GABAergic synapses anatomically and functionally, and GABA and ACh molecules are co-transmitted.Virág T. TakácsCsaba CserépDániel SchlingloffBalázs PósfaiAndrás SzőnyiKatalin E. SosZsuzsanna KörnyeiÁdám DénesAttila I. GulyásTamás F. FreundGábor NyiriNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Virág T. Takács
Csaba Cserép
Dániel Schlingloff
Balázs Pósfai
András Szőnyi
Katalin E. Sos
Zsuzsanna Környei
Ádám Dénes
Attila I. Gulyás
Tamás F. Freund
Gábor Nyiri
Co-transmission of acetylcholine and GABA regulates hippocampal states
description Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non-synaptically in volume transmission. Here, Takács and colleagues show cholinergic terminals juxtapose GABAergic synapses anatomically and functionally, and GABA and ACh molecules are co-transmitted.
format article
author Virág T. Takács
Csaba Cserép
Dániel Schlingloff
Balázs Pósfai
András Szőnyi
Katalin E. Sos
Zsuzsanna Környei
Ádám Dénes
Attila I. Gulyás
Tamás F. Freund
Gábor Nyiri
author_facet Virág T. Takács
Csaba Cserép
Dániel Schlingloff
Balázs Pósfai
András Szőnyi
Katalin E. Sos
Zsuzsanna Környei
Ádám Dénes
Attila I. Gulyás
Tamás F. Freund
Gábor Nyiri
author_sort Virág T. Takács
title Co-transmission of acetylcholine and GABA regulates hippocampal states
title_short Co-transmission of acetylcholine and GABA regulates hippocampal states
title_full Co-transmission of acetylcholine and GABA regulates hippocampal states
title_fullStr Co-transmission of acetylcholine and GABA regulates hippocampal states
title_full_unstemmed Co-transmission of acetylcholine and GABA regulates hippocampal states
title_sort co-transmission of acetylcholine and gaba regulates hippocampal states
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/9152c00a8484415dbce6f767cb36a338
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