Co-transmission of acetylcholine and GABA regulates hippocampal states
Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non-synaptically in volume transmission. Here, Takács and colleagues show cholinergic terminals juxtapose GABAergic synapses anatomically and functionally, and GABA and ACh molecules are co-transmitted.
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Nature Portfolio
2018
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oai:doaj.org-article:9152c00a8484415dbce6f767cb36a3382021-12-02T17:31:43ZCo-transmission of acetylcholine and GABA regulates hippocampal states10.1038/s41467-018-05136-12041-1723https://doaj.org/article/9152c00a8484415dbce6f767cb36a3382018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05136-1https://doaj.org/toc/2041-1723Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non-synaptically in volume transmission. Here, Takács and colleagues show cholinergic terminals juxtapose GABAergic synapses anatomically and functionally, and GABA and ACh molecules are co-transmitted.Virág T. TakácsCsaba CserépDániel SchlingloffBalázs PósfaiAndrás SzőnyiKatalin E. SosZsuzsanna KörnyeiÁdám DénesAttila I. GulyásTamás F. FreundGábor NyiriNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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Science Q Virág T. Takács Csaba Cserép Dániel Schlingloff Balázs Pósfai András Szőnyi Katalin E. Sos Zsuzsanna Környei Ádám Dénes Attila I. Gulyás Tamás F. Freund Gábor Nyiri Co-transmission of acetylcholine and GABA regulates hippocampal states |
description |
Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non-synaptically in volume transmission. Here, Takács and colleagues show cholinergic terminals juxtapose GABAergic synapses anatomically and functionally, and GABA and ACh molecules are co-transmitted. |
format |
article |
author |
Virág T. Takács Csaba Cserép Dániel Schlingloff Balázs Pósfai András Szőnyi Katalin E. Sos Zsuzsanna Környei Ádám Dénes Attila I. Gulyás Tamás F. Freund Gábor Nyiri |
author_facet |
Virág T. Takács Csaba Cserép Dániel Schlingloff Balázs Pósfai András Szőnyi Katalin E. Sos Zsuzsanna Környei Ádám Dénes Attila I. Gulyás Tamás F. Freund Gábor Nyiri |
author_sort |
Virág T. Takács |
title |
Co-transmission of acetylcholine and GABA regulates hippocampal states |
title_short |
Co-transmission of acetylcholine and GABA regulates hippocampal states |
title_full |
Co-transmission of acetylcholine and GABA regulates hippocampal states |
title_fullStr |
Co-transmission of acetylcholine and GABA regulates hippocampal states |
title_full_unstemmed |
Co-transmission of acetylcholine and GABA regulates hippocampal states |
title_sort |
co-transmission of acetylcholine and gaba regulates hippocampal states |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/9152c00a8484415dbce6f767cb36a338 |
work_keys_str_mv |
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1718380505612681216 |