The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells
MicroRNAs can posttranscriptionally repress multiple targets in a cell population. Here the authors use single-cell sequencing to investigate the effects of an individual miRNA on transcriptional heterogeneity and gene co-expression
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Nature Portfolio
2017
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oai:doaj.org-article:915b924b7b1a49c5860ec77d7652288d2021-12-02T17:01:21ZThe impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells10.1038/ncomms141262041-1723https://doaj.org/article/915b924b7b1a49c5860ec77d7652288d2017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14126https://doaj.org/toc/2041-1723MicroRNAs can posttranscriptionally repress multiple targets in a cell population. Here the authors use single-cell sequencing to investigate the effects of an individual miRNA on transcriptional heterogeneity and gene co-expressionGennaro GambardellaAnnamaria CarissimoAmy ChenLuisa CutilloTomasz J. NowakowskiDiego di BernardoRobert BlellochNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q Gennaro Gambardella Annamaria Carissimo Amy Chen Luisa Cutillo Tomasz J. Nowakowski Diego di Bernardo Robert Blelloch The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells |
description |
MicroRNAs can posttranscriptionally repress multiple targets in a cell population. Here the authors use single-cell sequencing to investigate the effects of an individual miRNA on transcriptional heterogeneity and gene co-expression |
format |
article |
author |
Gennaro Gambardella Annamaria Carissimo Amy Chen Luisa Cutillo Tomasz J. Nowakowski Diego di Bernardo Robert Blelloch |
author_facet |
Gennaro Gambardella Annamaria Carissimo Amy Chen Luisa Cutillo Tomasz J. Nowakowski Diego di Bernardo Robert Blelloch |
author_sort |
Gennaro Gambardella |
title |
The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells |
title_short |
The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells |
title_full |
The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells |
title_fullStr |
The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells |
title_full_unstemmed |
The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells |
title_sort |
impact of micrornas on transcriptional heterogeneity and gene co-expression across single embryonic stem cells |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/915b924b7b1a49c5860ec77d7652288d |
work_keys_str_mv |
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1718382159405776896 |