CRISPR Generated SIX6 and POU4F2 Reporters Allow Identification of Brain and Optic Transcriptional Differences in Human PSC-Derived Organoids

QR Code

CRISPR Generated SIX6 and POU4F2 Reporters Allow Identification of Brain and Optic Transcriptional Differences in Human PSC-Derived Organoids

Human pluripotent stem cells (PSCs) represent a powerful tool to investigate human eye development and disease. When grown in 3D, they can self-assemble into laminar organized retinas; however, variation in the size, shape and composition of individual organoids exists. Neither the microenvironment...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Karl J. Wahlin, Jie Cheng, Shawna L. Jurlina, Melissa K. Jones, Nicholas R. Dash, Anna Ogata, Nawal Kibria, Sunayan Ray, Kiara C. Eldred, Catherine Kim, Jacob S. Heng, Jenny Phillips, Robert J. Johnston, David M. Gamm, Cynthia Berlinicke, Donald J. Zack
Format:	article
Langue:	EN
Publié:	Frontiers Media S.A. 2021
Sujets:	optic microenvironment SIX6 Pou4f2 hypoxia vesicle Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/9163c7a815ae44529b224062f12f13fe
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

MicroRNA-107 is a novel tumor suppressor targeting POU3F2 in melanoma
par: Zhao,Guizhi, et autres
Publié: (2020)

Converging Effects of Three Different Endocrine Disrupters on Sox and Pou Gene Expression in Developing Rat Hippocampus: Possible Role of microRNA in Sex Differences
par: Walter Lichtensteiger, et autres
Publié: (2021)

POU class 2 homeobox associating factor 1 (POU2AF1) participates in abdominal aortic aneurysm enlargement based on integrated bioinformatics analysis
par: Jinze Meng, et autres
Publié: (2021)

De la revolución a la contra-revolución : ideología y pragmatismo en las Grand Strategies de la administración Bush /
par: Zack, Fernando
Publié: (2008)

Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells
par: Bhise NS, et autres
Publié: (2013)

Congenital hypopituitarism due to novel compound heterozygous POU1F1 gene mutation: A case report and review of the literature
par: Wei-Yu Chen, et autres
Publié: (2021)

mSphere of Influence: Considering Complex Mutational Processes That Shape Microbial Virulence
par: Matthew Zack Anderson
Publié: (2019)

HPV-16 E2/E6 and POU5F1B as Biomarkers to Determine Cervical High-Grade Squamous Lesions and More
par: Chen L, et autres
Publié: (2020)

Revisión de la implementación de Lean Six Sigma en Instituciones de Educación Superior
par: Guerrero Moreno,David Rodrigo, et autres
Publié: (2019)

Application of the random forest algorithm to Streptococcus pyogenes response regulator allele variation: from machine learning to evolutionary models
par: Sean J. Buckley, et autres
Publié: (2021)

The distribution and lifetime of powerful radio galaxies as a function of environment and redshift
par: David Garofalo, et autres
Publié: (2018)

Implementation and Control of Six-Phase Induction Motor Driven by a Three-Phase Supply
par: Mohamed I. Abdelwanis, et autres
Publié: (2021)

Lean Six Sigma en pequeñas y medianas empresas: un enfoque metodológico
par: Felizzola Jiménez,Heriberto, et autres
Publié: (2014)

Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells
par: Karl J. Wahlin, et autres
Publié: (2017)

Nanopore sequencing and de novo assembly of a misidentified Camelpox vaccine reveals putative epigenetic modifications and alternate protein signal peptides
par: Zack Saud, et autres
Publié: (2021)

Application of Six Sigma in a company Automotive in Morocco
par: Achibat Fatima Ezzahra, et autres
Publié: (2021)

Generation of a rod-specific NRL reporter line in human pluripotent stem cells
par: M. Joseph Phillips, et autres
Publié: (2018)

Pathogenicity of <named-content content-type="genus-species">Serratia marcescens</named-content> Strains in Honey Bees
par: Kasie Raymann, et autres
Publié: (2018)

Correction for Raymann et al., “Pathogenicity of <named-content content-type="genus-species">Serratia marcescens</named-content> Strains in Honey Bees”
par: Kasie Raymann, et autres
Publié: (2019)

Evaluation of moxifloxacin in canine and non‐human primate telemetry assays: Comparison of QTc interval prolongation by timepoint and concentration‐QTc analysis
par: Ray W. Chui, et autres
Publié: (2021)

Features and prospects of implementation of the integrated Lean Six Sigma methodology at the enterprise
par: N. N. Trofimova
Publié: (2021)

Protein delivery nanosystem of six-arm copolymer poly(ε-caprolactone)–poly(ethylene glycol) for long-term sustained release
par: Duan JW, et autres
Publié: (2018)

Protein-Mediated and RNA-Based Origins of Replication of Extrachromosomal Mycobacterial Prophages
par: Katherine S. Wetzel, et autres
Publié: (2020)

Migration and winter distribution of the Chestnutcollared Longspur
par: Ellison Kevin, et autres
Publié: (2017)

Engineered Type Six Secretion Systems Deliver Active Exogenous Effectors and Cre Recombinase
par: Steven J. Hersch, et autres
Publié: (2021)

Darśana, Philosophy and Religion in Pre-modern India
par: Ramkrishna Bhattacharya
Publié: (2016)

Sigma metrics of Alinity ci system – a study on thirty-nine clinical chemistry and immunoassay parameters
par: Kanani Fatima Zehra, et autres
Publié: (2021)

The Use of Lean Six Sigma for Improving Availability of and Access to Emergency Department Data to Facilitate Patient Flow
par: Ailish Daly, et autres
Publié: (2021)

Strengthening Hospital Capacity for the COVID-19 Pandemic: Implementation of Electronic Patient Discharge
par: Hossein Ebrahimipour, et autres
Publié: (2021)

Using Lean Six Sigma to Redesign the Supply Chain to the Operating Room Department of a Private Hospital to Reduce Associated Costs and Release Nursing Time to Care
par: Lisa O’Mahony, et autres
Publié: (2021)

Multicentennial record of Labrador Sea primary productivity and sea-ice variability archived in coralline algal barium
par: P. Chan, et autres
Publié: (2017)

A process model to support automated measurement and detection of out-of-bounds events in a hospital laboratory process
par: Costello,Claire, et autres
Publié: (2009)

Lean Six Sigma Redesign of a Process for Healthcare Mandatory Education in Basic Life Support—A Pilot Study
par: Anne Dempsey, et autres
Publié: (2021)

Redesigning the Process for Scheduling Elective Orthopaedic Surgery: A Combined Lean Six Sigma and Person-Centred Approach
par: Ailish Daly, et autres
Publié: (2021)

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration
par: Jie Wang, et autres
Publié: (2018)

Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells
par: Xitiz Chamling, et autres
Publié: (2021)

A Six-Sigma DMAIC Approach to Improve the Sales Process of a Technology Start-Up
par: Desy Wartati, et autres
Publié: (2021)

Releasing Operating Room Nursing Time to Care through the Reduction of Surgical Case Preparation Time: A Lean Six Sigma Pilot Study
par: Patricia Egan, et autres
Publié: (2021)

MODERN APPROACHES TO PROJECT MANAGEMENT
par: Marina Viktorovna Korshikova, et autres
Publié: (2020)

The use of effector gene based-markers to facilitate identification of Fusarium sp. infected shallot in Java, Indonesia
par: Lina Herlina, et autres
Publié: (2020)