Systematic Analysis of REBASE Identifies Numerous Type I Restriction-Modification Systems with Duplicated, Distinct <italic toggle="yes">hsdS</italic> Specificity Genes That Can Switch System Specificity by Recombination

Systematic Analysis of REBASE Identifies Numerous Type I Restriction-Modification Systems with Duplicated, Distinct <italic toggle="yes">hsdS</italic> Specificity Genes That Can Switch System Specificity by Recombination

ABSTRACT N6-Adenine DNA methyltransferases associated with some Type I and Type III restriction-modification (R-M) systems are able to undergo phase variation, randomly switching expression ON or OFF by varying the length of locus-encoded simple sequence repeats (SSRs). This variation of methyltrans...

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Autores principales: John M. Atack, Chengying Guo, Thomas Litfin, Long Yang, Patrick J. Blackall, Yaoqi Zhou, Michael P. Jennings
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
hsdS
phase variation
phasevarion
restriction-modification
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/91693bc9f96b4c51acd0bbffc06d674a
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