Conversion of anilines to chiral benzylic amines via formal one-carbon insertion into aromatic C–N bonds

Atom insertion into aromatic carbon-nitrogen (C-N) bonds is useful for the synthesis of nitrogen-containing molecules, but challenging due to the inert nature of these bonds. Here, the authors report one-carbon insertion into aromatic C-N bonds to directly convert anilines to chiral benzylic amines.

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Detalles Bibliográficos
Autores principales: Lei Li, Min Yang, Qiuqin He, Renhua Fan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/917c54f7881d431788d492095569abd1
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