Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus

The gene-battery model posits transposable elements (TEs) may becis-regulatory elements to control gene expression. Here, mouse-specific TEs are shown as binding sites for multiple collaborating transcription factors in embryonic stem cells, and act as cis-regulatory modules in synergistic fashion.

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Autores principales: Vasavi Sundaram, Mayank N. K. Choudhary, Erica Pehrsson, Xiaoyun Xing, Christopher Fiore, Manishi Pandey, Brett Maricque, Methma Udawatta, Duc Ngo, Yujie Chen, Asia Paguntalan, Tammy Ray, Ava Hughes, Barak A. Cohen, Ting Wang
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9182e1481f7b4fb78384a75c96e24065
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spelling oai:doaj.org-article:9182e1481f7b4fb78384a75c96e240652021-12-02T14:41:07ZFunctional cis-regulatory modules encoded by mouse-specific endogenous retrovirus10.1038/ncomms145502041-1723https://doaj.org/article/9182e1481f7b4fb78384a75c96e240652017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14550https://doaj.org/toc/2041-1723The gene-battery model posits transposable elements (TEs) may becis-regulatory elements to control gene expression. Here, mouse-specific TEs are shown as binding sites for multiple collaborating transcription factors in embryonic stem cells, and act as cis-regulatory modules in synergistic fashion.Vasavi SundaramMayank N. K. ChoudharyErica PehrssonXiaoyun XingChristopher FioreManishi PandeyBrett MaricqueMethma UdawattaDuc NgoYujie ChenAsia PaguntalanTammy RayAva HughesBarak A. CohenTing WangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Vasavi Sundaram
Mayank N. K. Choudhary
Erica Pehrsson
Xiaoyun Xing
Christopher Fiore
Manishi Pandey
Brett Maricque
Methma Udawatta
Duc Ngo
Yujie Chen
Asia Paguntalan
Tammy Ray
Ava Hughes
Barak A. Cohen
Ting Wang
Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus
description The gene-battery model posits transposable elements (TEs) may becis-regulatory elements to control gene expression. Here, mouse-specific TEs are shown as binding sites for multiple collaborating transcription factors in embryonic stem cells, and act as cis-regulatory modules in synergistic fashion.
format article
author Vasavi Sundaram
Mayank N. K. Choudhary
Erica Pehrsson
Xiaoyun Xing
Christopher Fiore
Manishi Pandey
Brett Maricque
Methma Udawatta
Duc Ngo
Yujie Chen
Asia Paguntalan
Tammy Ray
Ava Hughes
Barak A. Cohen
Ting Wang
author_facet Vasavi Sundaram
Mayank N. K. Choudhary
Erica Pehrsson
Xiaoyun Xing
Christopher Fiore
Manishi Pandey
Brett Maricque
Methma Udawatta
Duc Ngo
Yujie Chen
Asia Paguntalan
Tammy Ray
Ava Hughes
Barak A. Cohen
Ting Wang
author_sort Vasavi Sundaram
title Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus
title_short Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus
title_full Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus
title_fullStr Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus
title_full_unstemmed Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus
title_sort functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/9182e1481f7b4fb78384a75c96e24065
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