Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide

The permeability barrier of nuclear pore complexes blocks passage of inert macromolecules but allows rapid, receptor-mediated, and RanGTPase-driven transport of cargoes up to ribosome size. The authors now show that such a barrier can be faithfully recapitulated by an ultimately simplified FG phase...

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Autores principales:	Sheung Chun Ng, Thomas Güttler, Dirk Görlich
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/918341fbe77b4e0e801baba80a0b4533
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spelling	oai:doaj.org-article:918341fbe77b4e0e801baba80a0b45332021-12-02T14:34:05ZRecapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide10.1038/s41467-021-24292-52041-1723https://doaj.org/article/918341fbe77b4e0e801baba80a0b45332021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24292-5https://doaj.org/toc/2041-1723The permeability barrier of nuclear pore complexes blocks passage of inert macromolecules but allows rapid, receptor-mediated, and RanGTPase-driven transport of cargoes up to ribosome size. The authors now show that such a barrier can be faithfully recapitulated by an ultimately simplified FG phase assembled solely from a tandemly repeated 12mer GLFG peptide.Sheung Chun NgThomas GüttlerDirk GörlichNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sheung Chun Ng Thomas Güttler Dirk Görlich Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide
description	The permeability barrier of nuclear pore complexes blocks passage of inert macromolecules but allows rapid, receptor-mediated, and RanGTPase-driven transport of cargoes up to ribosome size. The authors now show that such a barrier can be faithfully recapitulated by an ultimately simplified FG phase assembled solely from a tandemly repeated 12mer GLFG peptide.
format	article
author	Sheung Chun Ng Thomas Güttler Dirk Görlich
author_facet	Sheung Chun Ng Thomas Güttler Dirk Görlich
author_sort	Sheung Chun Ng
title	Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide
title_short	Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide
title_full	Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide
title_fullStr	Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide
title_full_unstemmed	Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide
title_sort	recapitulation of selective nuclear import and export with a perfectly repeated 12mer glfg peptide
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/918341fbe77b4e0e801baba80a0b4533
work_keys_str_mv	AT sheungchunng recapitulationofselectivenuclearimportandexportwithaperfectlyrepeated12merglfgpeptide AT thomasguttler recapitulationofselectivenuclearimportandexportwithaperfectlyrepeated12merglfgpeptide AT dirkgorlich recapitulationofselectivenuclearimportandexportwithaperfectlyrepeated12merglfgpeptide
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Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide

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