Cholesterol oxidase is indispensable in the pathogenesis of Mycobacterium tuberculosis.

Cholesterol oxidase is indispensable in the pathogenesis of Mycobacterium tuberculosis.

Despite considerable research effort, the molecular mechanisms of Mycobacterium tuberculosis (Mtb) virulence remain unclear. Cholesterol oxidase (ChoD), an extracellular enzyme capable of converting cholesterol to its 3-keto-4-ene derivative, cholestenone, has been proposed to play a role in the vir...

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Autores principales: Magdalena Klink, Marta Brzezinska, Izabela Szulc, Anna Brzostek, Michal Kielbik, Zofia Sulowska, Jaroslaw Dziadek
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/918764a3e5234a7da9e132194adf96da
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