Upgrading ketone synthesis direct from carboxylic acids and organohalides
Due to their abundance and importance in organic chemistry, development of methods for ketone synthesis is essential. Here, the authors report a photoredox, nickel and phosphoranyl radical synergistic cross-electrophile coupling of aromatic acids and aryl/alkyl bromides to directly synthesise ketone...
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Nature Portfolio
2020
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oai:doaj.org-article:918a6d6aace14057b1822f8b673afe1c2021-12-02T16:10:52ZUpgrading ketone synthesis direct from carboxylic acids and organohalides10.1038/s41467-020-17224-22041-1723https://doaj.org/article/918a6d6aace14057b1822f8b673afe1c2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17224-2https://doaj.org/toc/2041-1723Due to their abundance and importance in organic chemistry, development of methods for ketone synthesis is essential. Here, the authors report a photoredox, nickel and phosphoranyl radical synergistic cross-electrophile coupling of aromatic acids and aryl/alkyl bromides to directly synthesise ketones.Rehanguli RuziKai LiuChengjian ZhuJin XieNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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Science Q Rehanguli Ruzi Kai Liu Chengjian Zhu Jin Xie Upgrading ketone synthesis direct from carboxylic acids and organohalides |
description |
Due to their abundance and importance in organic chemistry, development of methods for ketone synthesis is essential. Here, the authors report a photoredox, nickel and phosphoranyl radical synergistic cross-electrophile coupling of aromatic acids and aryl/alkyl bromides to directly synthesise ketones. |
format |
article |
author |
Rehanguli Ruzi Kai Liu Chengjian Zhu Jin Xie |
author_facet |
Rehanguli Ruzi Kai Liu Chengjian Zhu Jin Xie |
author_sort |
Rehanguli Ruzi |
title |
Upgrading ketone synthesis direct from carboxylic acids and organohalides |
title_short |
Upgrading ketone synthesis direct from carboxylic acids and organohalides |
title_full |
Upgrading ketone synthesis direct from carboxylic acids and organohalides |
title_fullStr |
Upgrading ketone synthesis direct from carboxylic acids and organohalides |
title_full_unstemmed |
Upgrading ketone synthesis direct from carboxylic acids and organohalides |
title_sort |
upgrading ketone synthesis direct from carboxylic acids and organohalides |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/918a6d6aace14057b1822f8b673afe1c |
work_keys_str_mv |
AT rehanguliruzi upgradingketonesynthesisdirectfromcarboxylicacidsandorganohalides AT kailiu upgradingketonesynthesisdirectfromcarboxylicacidsandorganohalides AT chengjianzhu upgradingketonesynthesisdirectfromcarboxylicacidsandorganohalides AT jinxie upgradingketonesynthesisdirectfromcarboxylicacidsandorganohalides |
_version_ |
1718384423185940480 |