Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides

Direct synthesis of aryl amines from nitroarenes avoids the waste and potential functional group incompatibility of first reducing to anilines. Here, the authors report an iron catalysed reductive coupling of nitroarenes with alkyl halides to form a wide range of (hetero)aromatic amines.

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Autores principales:	Chi Wai Cheung, Xile Hu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/918da62c7b424920b2c4918e56092f1d
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spelling	oai:doaj.org-article:918da62c7b424920b2c4918e56092f1d2021-12-02T16:50:56ZAmine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides10.1038/ncomms124942041-1723https://doaj.org/article/918da62c7b424920b2c4918e56092f1d2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12494https://doaj.org/toc/2041-1723Direct synthesis of aryl amines from nitroarenes avoids the waste and potential functional group incompatibility of first reducing to anilines. Here, the authors report an iron catalysed reductive coupling of nitroarenes with alkyl halides to form a wide range of (hetero)aromatic amines.Chi Wai CheungXile HuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chi Wai Cheung Xile Hu Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides
description	Direct synthesis of aryl amines from nitroarenes avoids the waste and potential functional group incompatibility of first reducing to anilines. Here, the authors report an iron catalysed reductive coupling of nitroarenes with alkyl halides to form a wide range of (hetero)aromatic amines.
format	article
author	Chi Wai Cheung Xile Hu
author_facet	Chi Wai Cheung Xile Hu
author_sort	Chi Wai Cheung
title	Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides
title_short	Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides
title_full	Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides
title_fullStr	Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides
title_full_unstemmed	Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides
title_sort	amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/918da62c7b424920b2c4918e56092f1d
work_keys_str_mv	AT chiwaicheung aminesynthesisviaironcatalysedreductivecouplingofnitroareneswithalkylhalides AT xilehu aminesynthesisviaironcatalysedreductivecouplingofnitroareneswithalkylhalides
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Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides

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