Neoplastic transformation of T lymphocytes through transgenic expression of a virus host modification protein.
Virus host evasion genes are ready-made tools for gene manipulation and therapy. In this work we have assessed the impact in vivo of the evasion gene A238L of the African Swine Fever Virus, a gene which inhibits transcription mediated by both NF-κB and NFAT. The A238L gene has been selectively expre...
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Autores principales: | Sílvia Cristina Paiva Almeida, Vivian Leite de Oliveira, Sónia Ventura, Margarita Bofill, Robert Michael Evans Parkhouse |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/919913ffb40a45f39bb004054ff9f018 |
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