Neoplastic transformation of T lymphocytes through transgenic expression of a virus host modification protein.

Virus host evasion genes are ready-made tools for gene manipulation and therapy. In this work we have assessed the impact in vivo of the evasion gene A238L of the African Swine Fever Virus, a gene which inhibits transcription mediated by both NF-κB and NFAT. The A238L gene has been selectively expre...

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Autores principales: Sílvia Cristina Paiva Almeida, Vivian Leite de Oliveira, Sónia Ventura, Margarita Bofill, Robert Michael Evans Parkhouse
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/919913ffb40a45f39bb004054ff9f018
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