Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors
Establishment of the outer blood-retina barrier is a hallmark of retinal development but the contribution of choroid endothelial cells (ECs) is not known. Here the authors show in the developing mouse retina that ECs remodel the basement membrane and lead to enhanced barrier function of retinal epit...
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Autores principales: | Ignacio Benedicto, Guillermo L. Lehmann, Michael Ginsberg, Daniel J. Nolan, Rohan Bareja, Olivier Elemento, Zelda Salfati, Nazia M. Alam, Glen T. Prusky, Pierre Llanos, Sina Y. Rabbany, Arvydas Maminishkis, Sheldon S. Miller, Shahin Rafii, Enrique Rodriguez-Boulan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/919b83179e8542b08aff5bc2e85e591a |
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