Single olfactory receptors set odor detection thresholds

Odorous chemicals broadly activate subsets of olfactory receptors in the nose, but how individual receptors contribute to behavioral sensitivity is not clear. Here, the authors demonstrate that detection thresholds in mice are set solely by the highest affinity receptor for a given odorant.

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Autores principales:	Adam Dewan, Annika Cichy, Jingji Zhang, Kayla Miguel, Paul Feinstein, Dmitry Rinberg, Thomas Bozza
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/919ce589a86f4f4b8f1ee4be45132f62
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spelling	oai:doaj.org-article:919ce589a86f4f4b8f1ee4be45132f622021-12-02T16:49:32ZSingle olfactory receptors set odor detection thresholds10.1038/s41467-018-05129-02041-1723https://doaj.org/article/919ce589a86f4f4b8f1ee4be45132f622018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05129-0https://doaj.org/toc/2041-1723Odorous chemicals broadly activate subsets of olfactory receptors in the nose, but how individual receptors contribute to behavioral sensitivity is not clear. Here, the authors demonstrate that detection thresholds in mice are set solely by the highest affinity receptor for a given odorant.Adam DewanAnnika CichyJingji ZhangKayla MiguelPaul FeinsteinDmitry RinbergThomas BozzaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Adam Dewan Annika Cichy Jingji Zhang Kayla Miguel Paul Feinstein Dmitry Rinberg Thomas Bozza Single olfactory receptors set odor detection thresholds
description	Odorous chemicals broadly activate subsets of olfactory receptors in the nose, but how individual receptors contribute to behavioral sensitivity is not clear. Here, the authors demonstrate that detection thresholds in mice are set solely by the highest affinity receptor for a given odorant.
format	article
author	Adam Dewan Annika Cichy Jingji Zhang Kayla Miguel Paul Feinstein Dmitry Rinberg Thomas Bozza
author_facet	Adam Dewan Annika Cichy Jingji Zhang Kayla Miguel Paul Feinstein Dmitry Rinberg Thomas Bozza
author_sort	Adam Dewan
title	Single olfactory receptors set odor detection thresholds
title_short	Single olfactory receptors set odor detection thresholds
title_full	Single olfactory receptors set odor detection thresholds
title_fullStr	Single olfactory receptors set odor detection thresholds
title_full_unstemmed	Single olfactory receptors set odor detection thresholds
title_sort	single olfactory receptors set odor detection thresholds
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/919ce589a86f4f4b8f1ee4be45132f62
work_keys_str_mv	AT adamdewan singleolfactoryreceptorssetodordetectionthresholds AT annikacichy singleolfactoryreceptorssetodordetectionthresholds AT jingjizhang singleolfactoryreceptorssetodordetectionthresholds AT kaylamiguel singleolfactoryreceptorssetodordetectionthresholds AT paulfeinstein singleolfactoryreceptorssetodordetectionthresholds AT dmitryrinberg singleolfactoryreceptorssetodordetectionthresholds AT thomasbozza singleolfactoryreceptorssetodordetectionthresholds
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Single olfactory receptors set odor detection thresholds

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