Pioglitazone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome.

Pioglitazone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome.

Insulin resistance is a common metabolic abnormality in women with PCOS and leads to an elevated risk of type 2 diabetes. Studies have shown that thiazolidinediones (TZDs) improve metabolic disturbances in PCOS patients. We hypothesized that the effect of TZDs in PCOS is, in part, mediated by change...

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Main Authors: Vibe Skov, Dorte Glintborg, Steen Knudsen, Qihua Tan, Thomas Jensen, Torben A Kruse, Henning Beck-Nielsen, Kurt Højlund
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/91a52f2354ba4d80ab0891b2d6f27951
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