Pioglitazone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome.

Insulin resistance is a common metabolic abnormality in women with PCOS and leads to an elevated risk of type 2 diabetes. Studies have shown that thiazolidinediones (TZDs) improve metabolic disturbances in PCOS patients. We hypothesized that the effect of TZDs in PCOS is, in part, mediated by change...

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Autores principales: Vibe Skov, Dorte Glintborg, Steen Knudsen, Qihua Tan, Thomas Jensen, Torben A Kruse, Henning Beck-Nielsen, Kurt Højlund
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/91a52f2354ba4d80ab0891b2d6f27951
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