The role of metabotropic glutamate receptor 5 on the stromal cell-derived factor-1/CXCR4 system in oral cancer.

We have demonstrated that blocking CXCR4 may be a potent anti-metastatic therapy for CXCR4-related oral cancer. However, as CXCR4 antagonists are currently in clinical use to induce the mobilization of hematopoietic stem cells, continuous administration as an inhibitor for the metastasis may lead to...

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Autores principales: Nobuyuki Kuribayashi, Daisuke Uchida, Makoto Kinouchi, Natsumi Takamaru, Tetsuya Tamatani, Hirokazu Nagai, Youji Miyamoto
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/91a7947183a84313bed47fe9c50d1033
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