LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription

Little is known about the role of long lncRNAs in autophagy. The authors identify lncCAIF, and show that it suppresses cardiac autophagy and attenuates myocardial infarction by targeting p53 -mediated transcription of myocardin.

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Autores principales:	Cui-Yun Liu, Yu-Hui Zhang, Rui-Bei Li, Lu-Yu Zhou, Tao An, Rong-Cheng Zhang, Mei Zhai, Yan Huang, Kao-Wen Yan, Yan-Han Dong, Murugavel Ponnusamy, Chan Shan, Sheng Xu, Qi Wang, Yan-Hui Zhang, Jian Zhang, Kun Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/91b40ea4b8fa4e09ae60130d62e5d600
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spelling	oai:doaj.org-article:91b40ea4b8fa4e09ae60130d62e5d6002021-12-02T14:40:08ZLncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription10.1038/s41467-017-02280-y2041-1723https://doaj.org/article/91b40ea4b8fa4e09ae60130d62e5d6002018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02280-yhttps://doaj.org/toc/2041-1723Little is known about the role of long lncRNAs in autophagy. The authors identify lncCAIF, and show that it suppresses cardiac autophagy and attenuates myocardial infarction by targeting p53 -mediated transcription of myocardin.Cui-Yun LiuYu-Hui ZhangRui-Bei LiLu-Yu ZhouTao AnRong-Cheng ZhangMei ZhaiYan HuangKao-Wen YanYan-Han DongMurugavel PonnusamyChan ShanSheng XuQi WangYan-Hui ZhangJian ZhangKun WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cui-Yun Liu Yu-Hui Zhang Rui-Bei Li Lu-Yu Zhou Tao An Rong-Cheng Zhang Mei Zhai Yan Huang Kao-Wen Yan Yan-Han Dong Murugavel Ponnusamy Chan Shan Sheng Xu Qi Wang Yan-Hui Zhang Jian Zhang Kun Wang LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription
description	Little is known about the role of long lncRNAs in autophagy. The authors identify lncCAIF, and show that it suppresses cardiac autophagy and attenuates myocardial infarction by targeting p53 -mediated transcription of myocardin.
format	article
author	Cui-Yun Liu Yu-Hui Zhang Rui-Bei Li Lu-Yu Zhou Tao An Rong-Cheng Zhang Mei Zhai Yan Huang Kao-Wen Yan Yan-Han Dong Murugavel Ponnusamy Chan Shan Sheng Xu Qi Wang Yan-Hui Zhang Jian Zhang Kun Wang
author_facet	Cui-Yun Liu Yu-Hui Zhang Rui-Bei Li Lu-Yu Zhou Tao An Rong-Cheng Zhang Mei Zhai Yan Huang Kao-Wen Yan Yan-Han Dong Murugavel Ponnusamy Chan Shan Sheng Xu Qi Wang Yan-Hui Zhang Jian Zhang Kun Wang
author_sort	Cui-Yun Liu
title	LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription
title_short	LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription
title_full	LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription
title_fullStr	LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription
title_full_unstemmed	LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription
title_sort	lncrna caif inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/91b40ea4b8fa4e09ae60130d62e5d600
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LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription

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