In Vivo and In Vitro Models of Hepatocellular Carcinoma: Current Strategies for Translational Modeling

In Vivo and In Vitro Models of Hepatocellular Carcinoma: Current Strategies for Translational Modeling

Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third leading cause of cancer-related death globally. HCC is a complex multistep disease and usually emerges in the setting of chronic liver diseases. The molecular pathogenesis of HCC varies according to the etiology,...

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Main Authors: Guilherme Ribeiro Romualdo, Kaat Leroy, Cícero Júlio Silva Costa, Gabriel Bacil Prata, Bart Vanderborght, Tereza Cristina da Silva, Luís Fernando Barbisan, Wellington Andraus, Lindsey Devisscher, Niels Olsen Saraiva Câmara, Mathieu Vinken, Bruno Cogliati
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
hepatocarcinogenesis
liver cancer
animal model
cell culture
gene mutation
epigenetic alteration
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/91bcbda415674b97aaf077363f4732ed
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https://doaj.org/article/91bcbda415674b97aaf077363f4732ed

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