An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y

Bacterial RNA degradation is typically initiated by endoribonucleases and followed by exoribonucleases. Here the authors report the targetome of endoRNase Y in Streptococcus pyogenes, revealing the interplay between RNase Y and 3′-to-5′ exoribonuclease PNPase and YhaM.

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Autores principales: Laura Broglia, Anne-Laure Lécrivain, Thibaud T. Renault, Karin Hahnke, Rina Ahmed-Begrich, Anaïs Le Rhun, Emmanuelle Charpentier
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/91cd2b74eef244269a407fef7ba055c4
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spelling oai:doaj.org-article:91cd2b74eef244269a407fef7ba055c42021-12-02T16:50:02ZAn RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y10.1038/s41467-020-15387-62041-1723https://doaj.org/article/91cd2b74eef244269a407fef7ba055c42020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15387-6https://doaj.org/toc/2041-1723Bacterial RNA degradation is typically initiated by endoribonucleases and followed by exoribonucleases. Here the authors report the targetome of endoRNase Y in Streptococcus pyogenes, revealing the interplay between RNase Y and 3′-to-5′ exoribonuclease PNPase and YhaM.Laura BrogliaAnne-Laure LécrivainThibaud T. RenaultKarin HahnkeRina Ahmed-BegrichAnaïs Le RhunEmmanuelle CharpentierNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Laura Broglia
Anne-Laure Lécrivain
Thibaud T. Renault
Karin Hahnke
Rina Ahmed-Begrich
Anaïs Le Rhun
Emmanuelle Charpentier
An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y
description Bacterial RNA degradation is typically initiated by endoribonucleases and followed by exoribonucleases. Here the authors report the targetome of endoRNase Y in Streptococcus pyogenes, revealing the interplay between RNase Y and 3′-to-5′ exoribonuclease PNPase and YhaM.
format article
author Laura Broglia
Anne-Laure Lécrivain
Thibaud T. Renault
Karin Hahnke
Rina Ahmed-Begrich
Anaïs Le Rhun
Emmanuelle Charpentier
author_facet Laura Broglia
Anne-Laure Lécrivain
Thibaud T. Renault
Karin Hahnke
Rina Ahmed-Begrich
Anaïs Le Rhun
Emmanuelle Charpentier
author_sort Laura Broglia
title An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y
title_short An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y
title_full An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y
title_fullStr An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y
title_full_unstemmed An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y
title_sort rna-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exornases and rnase y
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/91cd2b74eef244269a407fef7ba055c4
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