Association between hair cortisol concentration and metabolic syndrome

Metabolic syndrome (MetS) is a highly prevalent disorder defined as a cluster of cardiometabolic risk factors including obesity, hyperglycemia, hypertension, and dyslipidemia. It is believed that excessive cortisol secretion due to psychosocial stress-induced hypothalamic-pituitary-adrenal axis acti...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mazgelytė Eglė, Mažeikienė Asta, Burokienė Neringa, Matuzevičienė Rėda, Linkevičiūtė Aušra, Kučinskienė Zita Aušrelė, Karčiauskaitė Dovilė
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	cortisol metabolic syndrome psychosocial stress Medicine R
Acceso en línea:	https://doaj.org/article/91d329df5b574aee97b74f072a850520
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:91d329df5b574aee97b74f072a850520
record_format	dspace
spelling	oai:doaj.org-article:91d329df5b574aee97b74f072a8505202021-12-05T14:10:54ZAssociation between hair cortisol concentration and metabolic syndrome2391-546310.1515/med-2021-0298https://doaj.org/article/91d329df5b574aee97b74f072a8505202021-06-01T00:00:00Zhttps://doi.org/10.1515/med-2021-0298https://doaj.org/toc/2391-5463Metabolic syndrome (MetS) is a highly prevalent disorder defined as a cluster of cardiometabolic risk factors including obesity, hyperglycemia, hypertension, and dyslipidemia. It is believed that excessive cortisol secretion due to psychosocial stress-induced hypothalamic-pituitary-adrenal axis activation might be involved in the pathogenesis of MetS. We sought to explore the association between MetS and psychosocial risk factors, as well as cortisol concentration measured in different biological specimens including saliva, blood serum, and hair samples. The study was conducted on a sample of 163 young and middle-aged men who were divided into groups according to the presence of MetS. Hair cortisol concentration (HCC) was determined using high performance liquid chromatography with UV detection, while blood serum and salivary cortisol levels were measured by enzyme-linked immunoassay. Lipid metabolism biomarkers were determined using routine laboratory methods. Anthropometric and lifestyle characteristics, as well as self-reported psychosocial indicators, were also examined. Significantly higher HCC and lower social support level among participants with MetS compared with individuals without MetS were found. However, no significant differences in blood serum and salivary cortisol levels were observed between men with and without MetS. In conclusion, chronically elevated cortisol concentration might be a potential contributing factor to the development of MetS.Mazgelytė EglėMažeikienė AstaBurokienė NeringaMatuzevičienė RėdaLinkevičiūtė AušraKučinskienė Zita AušrelėKarčiauskaitė DovilėDe Gruyterarticlecortisolmetabolic syndromepsychosocial stressMedicineRENOpen Medicine, Vol 16, Iss 1, Pp 873-881 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cortisol metabolic syndrome psychosocial stress Medicine R
spellingShingle	cortisol metabolic syndrome psychosocial stress Medicine R Mazgelytė Eglė Mažeikienė Asta Burokienė Neringa Matuzevičienė Rėda Linkevičiūtė Aušra Kučinskienė Zita Aušrelė Karčiauskaitė Dovilė Association between hair cortisol concentration and metabolic syndrome
description	Metabolic syndrome (MetS) is a highly prevalent disorder defined as a cluster of cardiometabolic risk factors including obesity, hyperglycemia, hypertension, and dyslipidemia. It is believed that excessive cortisol secretion due to psychosocial stress-induced hypothalamic-pituitary-adrenal axis activation might be involved in the pathogenesis of MetS. We sought to explore the association between MetS and psychosocial risk factors, as well as cortisol concentration measured in different biological specimens including saliva, blood serum, and hair samples. The study was conducted on a sample of 163 young and middle-aged men who were divided into groups according to the presence of MetS. Hair cortisol concentration (HCC) was determined using high performance liquid chromatography with UV detection, while blood serum and salivary cortisol levels were measured by enzyme-linked immunoassay. Lipid metabolism biomarkers were determined using routine laboratory methods. Anthropometric and lifestyle characteristics, as well as self-reported psychosocial indicators, were also examined. Significantly higher HCC and lower social support level among participants with MetS compared with individuals without MetS were found. However, no significant differences in blood serum and salivary cortisol levels were observed between men with and without MetS. In conclusion, chronically elevated cortisol concentration might be a potential contributing factor to the development of MetS.
format	article
author	Mazgelytė Eglė Mažeikienė Asta Burokienė Neringa Matuzevičienė Rėda Linkevičiūtė Aušra Kučinskienė Zita Aušrelė Karčiauskaitė Dovilė
author_facet	Mazgelytė Eglė Mažeikienė Asta Burokienė Neringa Matuzevičienė Rėda Linkevičiūtė Aušra Kučinskienė Zita Aušrelė Karčiauskaitė Dovilė
author_sort	Mazgelytė Eglė
title	Association between hair cortisol concentration and metabolic syndrome
title_short	Association between hair cortisol concentration and metabolic syndrome
title_full	Association between hair cortisol concentration and metabolic syndrome
title_fullStr	Association between hair cortisol concentration and metabolic syndrome
title_full_unstemmed	Association between hair cortisol concentration and metabolic syndrome
title_sort	association between hair cortisol concentration and metabolic syndrome
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/91d329df5b574aee97b74f072a850520
work_keys_str_mv	AT mazgelyteegle associationbetweenhaircortisolconcentrationandmetabolicsyndrome AT mazeikieneasta associationbetweenhaircortisolconcentrationandmetabolicsyndrome AT burokieneneringa associationbetweenhaircortisolconcentrationandmetabolicsyndrome AT matuzevicienereda associationbetweenhaircortisolconcentrationandmetabolicsyndrome AT linkeviciuteausra associationbetweenhaircortisolconcentrationandmetabolicsyndrome AT kucinskienezitaausrele associationbetweenhaircortisolconcentrationandmetabolicsyndrome AT karciauskaitedovile associationbetweenhaircortisolconcentrationandmetabolicsyndrome
_version_	1718371616441761792

Association between hair cortisol concentration and metabolic syndrome

Ejemplares similares