Dynamics of SAS-I mediated H4 K16 acetylation during DNA replication in yeast.

The acetylation of H4 lysine 16 (H4 K16Ac) in Saccharomyces cerevisiae counteracts the binding of the heterochromatin complex SIR to chromatin and inhibits gene silencing. Contrary to other histone acetylation marks, the H4 K16Ac level is high on genes with low transcription, whereas highly transcri...

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Auteurs principaux: Mark Boltengagen, Anke Samel-Pommerencke, David Fechtig, Ann E Ehrenhofer-Murray
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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R
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Accès en ligne:https://doaj.org/article/91d6de2a251e46c69519fea549b9dd9f
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