Phenotypic Consequences of <i>SLC25A40-ABCB1</i> Fusions beyond Drug Resistance in High-Grade Serous Ovarian Cancer

QR Code

Phenotypic Consequences of <i>SLC25A40-ABCB1</i> Fusions beyond Drug Resistance in High-Grade Serous Ovarian Cancer

Despite high response rates to initial chemotherapy, the majority of women diagnosed with High-Grade Serous Ovarian Cancer (HGSOC) ultimately develop drug resistance within 1–2 years of treatment. We previously identified the most common mechanism of acquired resistance in HGSOC to date, transcripti...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Kathleen I. Pishas, Karla J. Cowley, Ahwan Pandey, Therese Hoang, Jessica A. Beach, Jennii Luu, Robert Vary, Lorey K. Smith, Carolyn E. Shembrey, Nineveh Rashoo, Madelynne O. White, Kaylene J. Simpson, Andrea Bild, Jason I. Griffiths, Dane Cheasley, Ian Campbell, David D. L. Bowtell, Elizabeth L. Christie
Format:	article
Langue:	EN
Publié:	MDPI AG 2021
Sujets:	<i>ABCB1</i> high-grade serous ovarian cancer drug resistance high-throughput drug screening Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Accès en ligne:	https://doaj.org/article/91d80e9c900e4f8aad1cb5d9d14cd353
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

The Relationship of <i>ABCB1/MDR1</i> and <i>CYP1A1</i> Variants with the Risk of Disease Development and Shortening of Overall Survival in Patients with Multiple Myeloma
par: Szymon Zmorzynski, et autres
Publié: (2021)

Tissue Type Differences in ABCB1 Expression and Paclitaxel Tissue Pharmacokinetics in Patients With Esophageal Cancer
par: Ruben A. G. van Eerden, et autres
Publié: (2021)

Loss of constitutive ABCB1 expression in breast cancer associated with worse prognosis
par: Delou JM, et autres
Publié: (2017)

<i>POLRMT</i> as a Novel Susceptibility Gene for Cardiotoxicity in Epirubicin Treatment of Breast Cancer Patients
par: Alejandro Velasco-Ruiz, et autres
Publié: (2021)

In Silico Survey and Characterization of <i>Babesia microti</i> Functional and Non-Functional Proteases
par: Monica Florin-Christensen, et autres
Publié: (2021)

Strategies for Nitrite Replacement in Fermented Sausages and Effect of High Pressure Processing against <i>Salmonella</i> spp. and <i>Listeria innocua</i>
par: Constanza Maria Lopez, et autres
Publié: (2021)

Voltage-Gated Sodium Channels as Potential Biomarkers and Therapeutic Targets for Epithelial Ovarian Cancer
par: Iris S. Brummelhuis, et autres
Publié: (2021)

Epigenetic Therapy Augments Classic Chemotherapy in Suppressing the Growth of 3D High-Grade Serous Ovarian Cancer Spheroids over an Extended Period of Time
par: Michelle Bilbao, et autres
Publié: (2021)

Biological and prognostic value of ETV5 in high-grade serous ovarian cancer
par: Lu Zhang, et autres
Publié: (2021)

ABCB1 polymorphism in clopidogrel-treated Montenegrin patients
par: Mugosa Snezana, et autres
Publié: (2021)

Efecto de variantes de los genes ABCB1 y CYP3A4 sobre la respuesta terapéutica a atorvastatina en individuos chilenos hipercolesterolémicos
par: Rosales Z,Alexy, et autres
Publié: (2011)

Characterization of a Novel Emaravirus Affecting Ash Species (<i>Fraxinus</i> spp.) in Europe
par: Thomas R. Gaskin, et autres
Publié: (2021)

Novel Nematode-Killing Protein-1 (Nkp-1) from a Marine Epiphytic Bacterium <i>Pseudoalteromonas tunicata</i>
par: Nor Hawani Salikin, et autres
Publié: (2021)

Anti-Obesity Effects of Combined <i>Cornus officinalis</i> and <i>Ribes fasciculatum</i> Extract in High-Fat Diet-Induced Obese Male Mice
par: Eunkuk Park, et autres
Publié: (2021)

Repurposing Eltrombopag for Multidrug Resistant <i>Staphylococcus aureus</i> Infections
par: Hyunjung Lee, et autres
Publié: (2021)

<i>APC</i> and <i>TP53</i> Mutations Predict Cetuximab Sensitivity across Consensus Molecular Subtypes
par: Ramya Thota, et autres
Publié: (2021)

Effect of Imipenem and Amikacin Combination against Multi-Drug Resistant <i>Pseudomonas aeruginosa</i>
par: Sara Mahmoud Farhan, et autres
Publié: (2021)

Transmission Dynamics of <i>Schistosoma haematobium</i> among School-Aged Children: A Cohort Study on Prevalence, Reinfection and Incidence after Mass Drug Administration in the White Nile State of Sudan
par: Yan Jin, et autres
Publié: (2021)

Pathogenic <i>BRCA</i> Variants as Biomarkers for Risk in Prostate Cancer
par: Ciara S. McNevin, et autres
Publié: (2021)

Analysis on Drug-Resistance-Associated Mutations among Multidrug-Resistant <i>Mycobacterium tuberculosis</i> Isolates in China
par: Hongbing Jia, et autres
Publié: (2021)

Estudio de la estabilidad química de comprimidos de ácido acetilsalicílico mediante un control de estanterías en farmacias de Concepción, Chile
par: Mennickent C,Sigrid, et autres
Publié: (2002)

Characteristics of <i>SlCML39</i>, a Tomato Calmodulin-like Gene, and Its Negative Role in High Temperature Tolerance of <i>Arabidopsis thaliana</i> during Germination and Seedling Growth
par: Haidong Ding, et autres
Publié: (2021)

Combined Therapeutic Effects of 131I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer
par: Wu P, et autres
Publié: (2020)

High Serpin Family A Member 10 Expression Confers Platinum Sensitivity and Is Associated With Survival Benefit in High-Grade Serous Ovarian Cancer: Based on Quantitative Proteomic Analysis
par: Wenwen Guo, et autres
Publié: (2021)

Effective Treatment against ESBL-Producing <i>Klebsiella pneumoniae</i> through Synergism of the Photodynamic Activity of Re (I) Compounds with Beta-Lactams
par: Iván A. González, et autres
Publié: (2021)

Metabolites of Siberian Raspberries: LC-MS Profile, Seasonal Variation, Antioxidant Activity and, Thermal Stability of <i>Rubus matsumuranus</i> Phenolome
par: Nina I. Kashchenko, et autres
Publié: (2021)

Identification and Characterization of New <i>Alu</i> Element Insertion in the <i>BRCA1</i> Exon 14 Associated with Hereditary Breast and Ovarian Cancer
par: Ahmed Bouras, et autres
Publié: (2021)

Melanoma Targeted Therapies beyond <i>BRAF</i>-Mutant Melanoma: Potential Druggable Mutations and Novel Treatment Approaches
par: Karam Khaddour, et autres
Publié: (2021)

Serum Untargeted Metabolism Reveals the Mechanism of <i>L. plantarum</i> ZDY2013 in Alleviating Kidney Injury Induced by High-Salt Diet
par: Cuixiang Wan, et autres
Publié: (2021)

The role of distinct BRD4 isoforms and their contribution to high-grade serous ovarian carcinoma pathogenesis
par: Ana Luiza Drumond-Bock, et autres
Publié: (2021)

Highly Expressed Progesterone Receptor B Isoform Increases Platinum Sensitivity and Survival of Ovarian High-Grade Serous Carcinoma
par: Hao Lin, et autres
Publié: (2021)

Clinical value of bioelectrical properties of cancerous tissue in advanced epithelial ovarian cancer patients
par: Paula Cunnea, et autres
Publié: (2018)

Development of a Multiplex Droplet Digital PCR Assay for the Detection of <i>Babesia</i>, <i>Bartonella</i>, and <i>Borrelia</i> Species
par: Ricardo Maggi, et autres
Publié: (2021)

An ATP-Binding Cassette Transporter, LaABCB11, Contributes to Alkaloid Transport in <i>Lycoris aurea</i>
par: Rong Wang, et autres
Publié: (2021)

The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice
par: Michael Jonathan Lehrke, et autres
Publié: (2021)

<i>BRCA</i> Variations Risk Assessment in Breast Cancers Using Different Artificial Intelligence Models
par: Niyazi Senturk, et autres
Publié: (2021)

<i>TP53</i> Mutation Is a Prognostic Factor in Lower Grade Glioma and May Influence Chemotherapy Efficacy
par: Humaira Noor, et autres
Publié: (2021)

Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer
par: Elizabeth L. Christie, et autres
Publié: (2019)

(<i>L</i>,⊙)-Fuzzy (<i>K</i>,<i>E</i>)-Soft Filter
par: Ahmed Aref Abd El-Latif, et autres
Publié: (2021)

Frequency of Common Variants in Genes Involved in Lipid-Lowering Response to Statins in Chilean Subjects with Hypercholesterolemia
par: Rosales,Alexy, et autres
Publié: (2011)