Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker

Linking protein components in a controlled manner is crucial for assembling protein nanostructures with pre-determined architecture. Here, the authors use a chemical cross-linker to fuse the terminal helices of two proteins into a single one, forcing the protein domains in a specific orientation.

Guardado en:

Detalles Bibliográficos
Autores principales:	Woo Hyeon Jeong, Haerim Lee, Dong Hyun Song, Jae-Hoon Eom, Sun Chang Kim, Hee-Seung Lee, Hayyoung Lee, Jie-Oh Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/92098307f65f4bc7afd1adb4559ec18b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:92098307f65f4bc7afd1adb4559ec18b
record_format	dspace
spelling	oai:doaj.org-article:92098307f65f4bc7afd1adb4559ec18b2021-12-02T15:34:52ZConnecting two proteins using a fusion alpha helix stabilized by a chemical cross linker10.1038/ncomms110312041-1723https://doaj.org/article/92098307f65f4bc7afd1adb4559ec18b2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11031https://doaj.org/toc/2041-1723Linking protein components in a controlled manner is crucial for assembling protein nanostructures with pre-determined architecture. Here, the authors use a chemical cross-linker to fuse the terminal helices of two proteins into a single one, forcing the protein domains in a specific orientation.Woo Hyeon JeongHaerim LeeDong Hyun SongJae-Hoon EomSun Chang KimHee-Seung LeeHayyoung LeeJie-Oh LeeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Woo Hyeon Jeong Haerim Lee Dong Hyun Song Jae-Hoon Eom Sun Chang Kim Hee-Seung Lee Hayyoung Lee Jie-Oh Lee Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker
description	Linking protein components in a controlled manner is crucial for assembling protein nanostructures with pre-determined architecture. Here, the authors use a chemical cross-linker to fuse the terminal helices of two proteins into a single one, forcing the protein domains in a specific orientation.
format	article
author	Woo Hyeon Jeong Haerim Lee Dong Hyun Song Jae-Hoon Eom Sun Chang Kim Hee-Seung Lee Hayyoung Lee Jie-Oh Lee
author_facet	Woo Hyeon Jeong Haerim Lee Dong Hyun Song Jae-Hoon Eom Sun Chang Kim Hee-Seung Lee Hayyoung Lee Jie-Oh Lee
author_sort	Woo Hyeon Jeong
title	Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker
title_short	Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker
title_full	Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker
title_fullStr	Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker
title_full_unstemmed	Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker
title_sort	connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/92098307f65f4bc7afd1adb4559ec18b
work_keys_str_mv	AT woohyeonjeong connectingtwoproteinsusingafusionalphahelixstabilizedbyachemicalcrosslinker AT haerimlee connectingtwoproteinsusingafusionalphahelixstabilizedbyachemicalcrosslinker AT donghyunsong connectingtwoproteinsusingafusionalphahelixstabilizedbyachemicalcrosslinker AT jaehooneom connectingtwoproteinsusingafusionalphahelixstabilizedbyachemicalcrosslinker AT sunchangkim connectingtwoproteinsusingafusionalphahelixstabilizedbyachemicalcrosslinker AT heeseunglee connectingtwoproteinsusingafusionalphahelixstabilizedbyachemicalcrosslinker AT hayyounglee connectingtwoproteinsusingafusionalphahelixstabilizedbyachemicalcrosslinker AT jieohlee connectingtwoproteinsusingafusionalphahelixstabilizedbyachemicalcrosslinker
_version_	1718386732701843456

Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker

Ejemplares similares