ADP-Ribosylation of NLRP3 by <named-content content-type="genus-species">Mycoplasma pneumoniae</named-content> CARDS Toxin Regulates Inflammasome Activity
ABSTRACT The inflammasome is a major regulator of inflammation through its activation of procaspase-1, which cleaves prointerleukin-1β (pro-IL-1β) into its mature form. IL-1β is a critical proinflammatory cytokine that dictates the severity of inflammation associated with a wide spectrum of inflamma...
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Auteurs principaux: | Santanu Bose, Jesus A. Segovia, Sudha R. Somarajan, Te-Hung Chang, T. R. Kannan, Joel B. Baseman |
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Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2014
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Accès en ligne: | https://doaj.org/article/921250cbe3eb4a59a1d28b355d922cee |
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