ADP-Ribosylation of NLRP3 by <named-content content-type="genus-species">Mycoplasma pneumoniae</named-content> CARDS Toxin Regulates Inflammasome Activity

ABSTRACT The inflammasome is a major regulator of inflammation through its activation of procaspase-1, which cleaves prointerleukin-1β (pro-IL-1β) into its mature form. IL-1β is a critical proinflammatory cytokine that dictates the severity of inflammation associated with a wide spectrum of inflamma...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Santanu Bose, Jesus A. Segovia, Sudha R. Somarajan, Te-Hung Chang, T. R. Kannan, Joel B. Baseman
Format: article
Langue:EN
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://doaj.org/article/921250cbe3eb4a59a1d28b355d922cee
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!