Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales

It is known that males have lower recombination rates than females over much of the genome but little is known about differences at a fine scale. Here the authors combine data from over 100,000 meioses and show that the majority of differences can be explained by variation in hotspot magnitude.

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Detalles Bibliográficos
Autores principales: Claude Bhérer, Christopher L. Campbell, Adam Auton
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9215582a8dca4aa4a5f01b64081c53b5
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Sumario:It is known that males have lower recombination rates than females over much of the genome but little is known about differences at a fine scale. Here the authors combine data from over 100,000 meioses and show that the majority of differences can be explained by variation in hotspot magnitude.