Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales

It is known that males have lower recombination rates than females over much of the genome but little is known about differences at a fine scale. Here the authors combine data from over 100,000 meioses and show that the majority of differences can be explained by variation in hotspot magnitude.

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Autores principales:	Claude Bhérer, Christopher L. Campbell, Adam Auton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9215582a8dca4aa4a5f01b64081c53b5
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spelling	oai:doaj.org-article:9215582a8dca4aa4a5f01b64081c53b52021-12-02T14:42:10ZRefined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales10.1038/ncomms149942041-1723https://doaj.org/article/9215582a8dca4aa4a5f01b64081c53b52017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14994https://doaj.org/toc/2041-1723It is known that males have lower recombination rates than females over much of the genome but little is known about differences at a fine scale. Here the authors combine data from over 100,000 meioses and show that the majority of differences can be explained by variation in hotspot magnitude.Claude BhérerChristopher L. CampbellAdam AutonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Claude Bhérer Christopher L. Campbell Adam Auton Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales
description	It is known that males have lower recombination rates than females over much of the genome but little is known about differences at a fine scale. Here the authors combine data from over 100,000 meioses and show that the majority of differences can be explained by variation in hotspot magnitude.
format	article
author	Claude Bhérer Christopher L. Campbell Adam Auton
author_facet	Claude Bhérer Christopher L. Campbell Adam Auton
author_sort	Claude Bhérer
title	Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales
title_short	Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales
title_full	Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales
title_fullStr	Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales
title_full_unstemmed	Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales
title_sort	refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9215582a8dca4aa4a5f01b64081c53b5
work_keys_str_mv	AT claudebherer refinedgeneticmapsrevealsexualdimorphisminhumanmeioticrecombinationatmultiplescales AT christopherlcampbell refinedgeneticmapsrevealsexualdimorphisminhumanmeioticrecombinationatmultiplescales AT adamauton refinedgeneticmapsrevealsexualdimorphisminhumanmeioticrecombinationatmultiplescales
_version_	1718389765309464576

Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales

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