Nonhomologous Recombination between Defective Poliovirus and Coxsackievirus Genomes Suggests a New Model of Genetic Plasticity for Picornaviruses

ABSTRACT Most of the circulating vaccine-derived polioviruses (cVDPVs) implicated in poliomyelitis outbreaks in Madagascar have been shown to be recombinants between the type 2 poliovirus (PV) strain of the oral polio vaccine (Sabin 2) and another species C human enterovirus (HEV-C), such as type 17...

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Bibliographic Details
Main Authors: Barbara Holmblat, Sophie Jégouic, Claire Muslin, Bruno Blondel, Marie-Line Joffret, Francis Delpeyroux
Format: article
Language:EN
Published: American Society for Microbiology 2014
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Online Access:https://doaj.org/article/922c28228bbe4f749ebd2eb5e446124d
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