CAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION

Background. Immune thrombocytopenia in children is not a rare disease. Currently, this diagnosis is found in 2 times more often than 5-10 years ago. Acute immune thrombocytopenia is increasingly taking on a chronic course. Aims. At present, it is impossible to predict the outcome of the disease. But...

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Autores principales:	N. N. Martynovich, O. P. Tolmacheva, V. A. Khyshova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2018
Materias:	purpura thrombocytopenic idiopathic Science Q
Acceso en línea:	https://doaj.org/article/92610f3f7a9e4b4aac80100b4d1e4a0d
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spelling	oai:doaj.org-article:92610f3f7a9e4b4aac80100b4d1e4a0d2021-11-23T06:14:41ZCAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION2541-94202587-959610.29413/ABS.2018-3.5.13https://doaj.org/article/92610f3f7a9e4b4aac80100b4d1e4a0d2018-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/712https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Background. Immune thrombocytopenia in children is not a rare disease. Currently, this diagnosis is found in 2 times more often than 5-10 years ago. Acute immune thrombocytopenia is increasingly taking on a chronic course. Aims. At present, it is impossible to predict the outcome of the disease. But the chronic course of the disease significantly reduces the quality of life of children and their parents. The purpose of the study is to determine the likely causes of the development and chronicity of the disease. Materials and Methods. A retrospective analysis of 433 case histories of the cancer department of the Regional Children’s Hospital in Irkutsk was conducted. Statistical processing of the received data was carried out with the help of the Matlab program and statistical package “Statistica 6.0”. Results. The main trigger factor is ARVI and vaccination against poliomyelitis. Sensitization to herpes viruses can be a provoking factor in the development of the disease when re-encountering the virus. The brighter the clinic, the more children receive immunoglobulin treatment and the disease often ends with complete recovery. Children with minimal clinical manifestations are treated with hormones and more often the disease passes into a chronic form. Conclusion. If the child is discharged from the hospital with only a clinical improvement, then there is a greater likelihood of a chronic process.N. N. MartynovichO. P. TolmachevaV. A. KhyshovaScientific Сentre for Family Health and Human Reproduction ProblemsarticlepurpurathrombocytopenicidiopathicScienceQRUActa Biomedica Scientifica, Vol 3, Iss 5, Pp 82-86 (2018)
institution	DOAJ
collection	DOAJ
language	RU
topic	purpura thrombocytopenic idiopathic Science Q
spellingShingle	purpura thrombocytopenic idiopathic Science Q N. N. Martynovich O. P. Tolmacheva V. A. Khyshova CAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION
description	Background. Immune thrombocytopenia in children is not a rare disease. Currently, this diagnosis is found in 2 times more often than 5-10 years ago. Acute immune thrombocytopenia is increasingly taking on a chronic course. Aims. At present, it is impossible to predict the outcome of the disease. But the chronic course of the disease significantly reduces the quality of life of children and their parents. The purpose of the study is to determine the likely causes of the development and chronicity of the disease. Materials and Methods. A retrospective analysis of 433 case histories of the cancer department of the Regional Children’s Hospital in Irkutsk was conducted. Statistical processing of the received data was carried out with the help of the Matlab program and statistical package “Statistica 6.0”. Results. The main trigger factor is ARVI and vaccination against poliomyelitis. Sensitization to herpes viruses can be a provoking factor in the development of the disease when re-encountering the virus. The brighter the clinic, the more children receive immunoglobulin treatment and the disease often ends with complete recovery. Children with minimal clinical manifestations are treated with hormones and more often the disease passes into a chronic form. Conclusion. If the child is discharged from the hospital with only a clinical improvement, then there is a greater likelihood of a chronic process.
format	article
author	N. N. Martynovich O. P. Tolmacheva V. A. Khyshova
author_facet	N. N. Martynovich O. P. Tolmacheva V. A. Khyshova
author_sort	N. N. Martynovich
title	CAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION
title_short	CAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION
title_full	CAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION
title_fullStr	CAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION
title_full_unstemmed	CAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION
title_sort	causes of development of acute and chronic thrombocytopenia in children of irkutsk region
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2018
url	https://doaj.org/article/92610f3f7a9e4b4aac80100b4d1e4a0d
work_keys_str_mv	AT nnmartynovich causesofdevelopmentofacuteandchronicthrombocytopeniainchildrenofirkutskregion AT optolmacheva causesofdevelopmentofacuteandchronicthrombocytopeniainchildrenofirkutskregion AT vakhyshova causesofdevelopmentofacuteandchronicthrombocytopeniainchildrenofirkutskregion
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CAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION

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