MIR337-3p Enhances Mycobacterial Pathogenicity Involving TLR4/MYD88 and STAT3 Signals, Impairing VDR Antimicrobial Response and Fast-Acting Immunity

Active form of vitamin D (VitD) enhances human innate immunity against Mycobacterium tuberculosis (Mtb) infection. Our previous studies showed that MIR337-3p was highly expressed in lymphocytes of tuberculosis (TB) patients. Here, we identified the mechanism of MIR337-3p in the regulation of fast-ac...

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Autores principales: Shanshan Liang, Guixian Huang, Tian Wu, Ying Peng, Xi Liu, Xuejiao Ji, Wei Sha, Feifei Wang, Ling Shen, Hongbo Shen
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/92613dd1b3004f67ba2d6c9aa61655b6
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