Canine neosporosis: perspectives on pathogenesis and management

Rodrigo C Silva,1 Gustavo P Machado2 1Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Starkville, MS, USA; 2Department of Internal Medicine and Surgery of Small Animals, Dr Munhoz Veterinary Hospital, Itápolis, Brazil Abst...

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Autores principales:	Silva RC, Machado GP
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Neosporosis Neospora caninum pathogenesis management dogs Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/926421b054d244569592789ffb09a760
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spelling	oai:doaj.org-article:926421b054d244569592789ffb09a7602021-12-02T03:50:52ZCanine neosporosis: perspectives on pathogenesis and management2230-2034https://doaj.org/article/926421b054d244569592789ffb09a7602016-04-01T00:00:00Zhttps://www.dovepress.com/canine-neosporosis-perspectives-on-pathogenesis-and-management-peer-reviewed-article-VMRRhttps://doaj.org/toc/2230-2034Rodrigo C Silva,1 Gustavo P Machado2 1Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Starkville, MS, USA; 2Department of Internal Medicine and Surgery of Small Animals, Dr Munhoz Veterinary Hospital, Itápolis, Brazil Abstract: Canine neosporosis is a worldwide disease caused by the obligate intracellular parasite protozoan Neospora caninum, manifesting mainly neurological symptoms. N. caninum has a heteroxenous life cycle and affects a wide range of warm-blooded animals. The domestic and wild canids are the definitive host of the parasite. They shed oocysts after ingestion of tissue cysts from infected intermediate hosts (ovine, equine, bovine, canine, and many other species), containing bradyzoites, or oocyst-contaminated water and food. The presence of dogs in farms is considered a risk factor for production animals. A wide range of diagnostic methods are currently available, but the most used is serology, ie, indirect fluorescent antibody test specific to the antibody detection in blood serum samples. No vaccine is available, but control strategies should be focused on the vertical and horizontal transmission of the parasite, ie, avoid feeding dogs with raw or undercooked meat, and taking care with water for human and animal consumption. No medicines to control the transplacental transmission are available yet. Keywords: neosporosis, Neospora caninum, pathogenesis, management, dogsSilva RCMachado GPDove Medical PressarticleNeosporosisNeospora caninumpathogenesismanagementdogsVeterinary medicineSF600-1100ENVeterinary Medicine: Research and Reports, Vol 2016, Iss Issue 1, Pp 59-70 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neosporosis Neospora caninum pathogenesis management dogs Veterinary medicine SF600-1100
spellingShingle	Neosporosis Neospora caninum pathogenesis management dogs Veterinary medicine SF600-1100 Silva RC Machado GP Canine neosporosis: perspectives on pathogenesis and management
description	Rodrigo C Silva,1 Gustavo P Machado2 1Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Starkville, MS, USA; 2Department of Internal Medicine and Surgery of Small Animals, Dr Munhoz Veterinary Hospital, Itápolis, Brazil Abstract: Canine neosporosis is a worldwide disease caused by the obligate intracellular parasite protozoan Neospora caninum, manifesting mainly neurological symptoms. N. caninum has a heteroxenous life cycle and affects a wide range of warm-blooded animals. The domestic and wild canids are the definitive host of the parasite. They shed oocysts after ingestion of tissue cysts from infected intermediate hosts (ovine, equine, bovine, canine, and many other species), containing bradyzoites, or oocyst-contaminated water and food. The presence of dogs in farms is considered a risk factor for production animals. A wide range of diagnostic methods are currently available, but the most used is serology, ie, indirect fluorescent antibody test specific to the antibody detection in blood serum samples. No vaccine is available, but control strategies should be focused on the vertical and horizontal transmission of the parasite, ie, avoid feeding dogs with raw or undercooked meat, and taking care with water for human and animal consumption. No medicines to control the transplacental transmission are available yet. Keywords: neosporosis, Neospora caninum, pathogenesis, management, dogs
format	article
author	Silva RC Machado GP
author_facet	Silva RC Machado GP
author_sort	Silva RC
title	Canine neosporosis: perspectives on pathogenesis and management
title_short	Canine neosporosis: perspectives on pathogenesis and management
title_full	Canine neosporosis: perspectives on pathogenesis and management
title_fullStr	Canine neosporosis: perspectives on pathogenesis and management
title_full_unstemmed	Canine neosporosis: perspectives on pathogenesis and management
title_sort	canine neosporosis: perspectives on pathogenesis and management
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/926421b054d244569592789ffb09a760
work_keys_str_mv	AT silvarc canineneosporosisperspectivesonpathogenesisandmanagement AT machadogp canineneosporosisperspectivesonpathogenesisandmanagement
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Canine neosporosis: perspectives on pathogenesis and management

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