MAJOR LYMPHOCYTE SUBPOPULATIONS IN COMBINED INFECTIONS HERPES VIRUS (HSV) AND VARIOUS FORMS OF TUBERCULOSIS

The goal of present work was to study main cell subpopulations of immune system, frequency of human herpes virus (HSV) type 1 activation, and presence of HSV in patients with tuberculosis (TB). We have shown an increased level of herpesvirus type 1 and type 2 manifestation in patients with different...

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Autor principal:	M. A. Karalyan
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	simplex virus tuberculosis immune system Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/926f1006056d433ab01e62bcb8b1982c
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spelling	oai:doaj.org-article:926f1006056d433ab01e62bcb8b1982c2021-11-18T08:03:37ZMAJOR LYMPHOCYTE SUBPOPULATIONS IN COMBINED INFECTIONS HERPES VIRUS (HSV) AND VARIOUS FORMS OF TUBERCULOSIS1563-06252313-741X10.15789/1563-0625-2010-1-2-139-142https://doaj.org/article/926f1006056d433ab01e62bcb8b1982c2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/58https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XThe goal of present work was to study main cell subpopulations of immune system, frequency of human herpes virus (HSV) type 1 activation, and presence of HSV in patients with tuberculosis (TB). We have shown an increased level of herpesvirus type 1 and type 2 manifestation in patients with different types of tuberculosis (TB). A statistically significant decrease in the CD4/CD8 ratio and in percentage of CD3+, CD4+ cells patients with certain clinical forms of TB was shown, as compared to the group with active HSV infection. The data obtained showed absence of correlation between TB-related reactions, HSV infection, and levels of HSV-specific antibodies. Deficient function of cells with natural killer (NK) activity, and decreased numbers of CD56+ cells have been also of shown. NK cells may be among most relevant components of immune reactions to HSV infection. Main role in HSV activation in the TB patients depends on deficiency of NK-like cells.M. A. KaralyanSPb RAACIarticlesimplex virustuberculosisimmune systemImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 1-2, Pp 139-142 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	simplex virus tuberculosis immune system Immunologic diseases. Allergy RC581-607
spellingShingle	simplex virus tuberculosis immune system Immunologic diseases. Allergy RC581-607 M. A. Karalyan MAJOR LYMPHOCYTE SUBPOPULATIONS IN COMBINED INFECTIONS HERPES VIRUS (HSV) AND VARIOUS FORMS OF TUBERCULOSIS
description	The goal of present work was to study main cell subpopulations of immune system, frequency of human herpes virus (HSV) type 1 activation, and presence of HSV in patients with tuberculosis (TB). We have shown an increased level of herpesvirus type 1 and type 2 manifestation in patients with different types of tuberculosis (TB). A statistically significant decrease in the CD4/CD8 ratio and in percentage of CD3+, CD4+ cells patients with certain clinical forms of TB was shown, as compared to the group with active HSV infection. The data obtained showed absence of correlation between TB-related reactions, HSV infection, and levels of HSV-specific antibodies. Deficient function of cells with natural killer (NK) activity, and decreased numbers of CD56+ cells have been also of shown. NK cells may be among most relevant components of immune reactions to HSV infection. Main role in HSV activation in the TB patients depends on deficiency of NK-like cells.
format	article
author	M. A. Karalyan
author_facet	M. A. Karalyan
author_sort	M. A. Karalyan
title	MAJOR LYMPHOCYTE SUBPOPULATIONS IN COMBINED INFECTIONS HERPES VIRUS (HSV) AND VARIOUS FORMS OF TUBERCULOSIS
title_short	MAJOR LYMPHOCYTE SUBPOPULATIONS IN COMBINED INFECTIONS HERPES VIRUS (HSV) AND VARIOUS FORMS OF TUBERCULOSIS
title_full	MAJOR LYMPHOCYTE SUBPOPULATIONS IN COMBINED INFECTIONS HERPES VIRUS (HSV) AND VARIOUS FORMS OF TUBERCULOSIS
title_fullStr	MAJOR LYMPHOCYTE SUBPOPULATIONS IN COMBINED INFECTIONS HERPES VIRUS (HSV) AND VARIOUS FORMS OF TUBERCULOSIS
title_full_unstemmed	MAJOR LYMPHOCYTE SUBPOPULATIONS IN COMBINED INFECTIONS HERPES VIRUS (HSV) AND VARIOUS FORMS OF TUBERCULOSIS
title_sort	major lymphocyte subpopulations in combined infections herpes virus (hsv) and various forms of tuberculosis
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/926f1006056d433ab01e62bcb8b1982c
work_keys_str_mv	AT makaralyan majorlymphocytesubpopulationsincombinedinfectionsherpesvirushsvandvariousformsoftuberculosis
_version_	1718422558713315328

MAJOR LYMPHOCYTE SUBPOPULATIONS IN COMBINED INFECTIONS HERPES VIRUS (HSV) AND VARIOUS FORMS OF TUBERCULOSIS

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