Body mass index is associated with type 2 diabetes mellitus in Chinese elderly

Qianping Zhao,1 Jari A Laukkanen,2,3 Qifu Li,4 Gang Li1 1Division of Cardiology, Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Institute of Public Health and Clinical Nutrition, University of Eastern Finlan...

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Autores principales:	Zhao Q, Laukkanen JA, Li Q, Li G
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	body mass index type 2 diabetes elderly aging Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/9271febabf4b4f07b3d9af9f65ddb641
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spelling	oai:doaj.org-article:9271febabf4b4f07b3d9af9f65ddb6412021-12-02T10:51:42ZBody mass index is associated with type 2 diabetes mellitus in Chinese elderly1178-1998https://doaj.org/article/9271febabf4b4f07b3d9af9f65ddb6412017-05-01T00:00:00Zhttps://www.dovepress.com/body-mass-index-is-associated-with-type-2-diabetes-mellitus-in-chinese-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Qianping Zhao,1 Jari A Laukkanen,2,3 Qifu Li,4 Gang Li1 1Division of Cardiology, Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland; 3Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland; 4Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China Background: There is limited information on the association between metabolic syndrome components including body mass index (BMI) and type 2 diabetes mellitus in elderly Chinese population. Therefore, we investigated whether components of metabolic syndrome are associated with type 2 diabetes mellitus in elderly. Methods: A total of 479 hospitalized patients (aged 65–95 years) with recently diagnosed type 2 diabetes mellitus were studied retrospectively in a cross-sectional study and compared with 183 subjects with prediabetes and 62 subjects without glucose metabolism abnormalities. Results: BMI (24.69±3.59 versus 23.92±3.08 and 23.56±3.25 kg/m2), blood pressure, cholesterol, triglyceride, liver enzymes and prevalence of fatty liver were higher in patients with type 2 diabetes mellitus as compared with elderly subjects with prediabetes or normal glucose metabolism separately (all P<0.05). Multivariable regression analysis showed that BMI was associated positively with insulin resistance and inversely with insulin sensitivity in type 2 diabetes mellitus group (all P<0.05). Conclusion: Higher BMI was associated with increased insulin resistance and decreased insulin sensitivity in elderly Asian population with type 2 diabetes mellitus. Keywords: body mass index, type 2 diabetes, elderly, agingZhao QLaukkanen JALi QLi GDove Medical Pressarticlebody mass indextype 2 diabeteselderlyagingGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 12, Pp 745-752 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	body mass index type 2 diabetes elderly aging Geriatrics RC952-954.6
spellingShingle	body mass index type 2 diabetes elderly aging Geriatrics RC952-954.6 Zhao Q Laukkanen JA Li Q Li G Body mass index is associated with type 2 diabetes mellitus in Chinese elderly
description	Qianping Zhao,1 Jari A Laukkanen,2,3 Qifu Li,4 Gang Li1 1Division of Cardiology, Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland; 3Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland; 4Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China Background: There is limited information on the association between metabolic syndrome components including body mass index (BMI) and type 2 diabetes mellitus in elderly Chinese population. Therefore, we investigated whether components of metabolic syndrome are associated with type 2 diabetes mellitus in elderly. Methods: A total of 479 hospitalized patients (aged 65–95 years) with recently diagnosed type 2 diabetes mellitus were studied retrospectively in a cross-sectional study and compared with 183 subjects with prediabetes and 62 subjects without glucose metabolism abnormalities. Results: BMI (24.69±3.59 versus 23.92±3.08 and 23.56±3.25 kg/m2), blood pressure, cholesterol, triglyceride, liver enzymes and prevalence of fatty liver were higher in patients with type 2 diabetes mellitus as compared with elderly subjects with prediabetes or normal glucose metabolism separately (all P<0.05). Multivariable regression analysis showed that BMI was associated positively with insulin resistance and inversely with insulin sensitivity in type 2 diabetes mellitus group (all P<0.05). Conclusion: Higher BMI was associated with increased insulin resistance and decreased insulin sensitivity in elderly Asian population with type 2 diabetes mellitus. Keywords: body mass index, type 2 diabetes, elderly, aging
format	article
author	Zhao Q Laukkanen JA Li Q Li G
author_facet	Zhao Q Laukkanen JA Li Q Li G
author_sort	Zhao Q
title	Body mass index is associated with type 2 diabetes mellitus in Chinese elderly
title_short	Body mass index is associated with type 2 diabetes mellitus in Chinese elderly
title_full	Body mass index is associated with type 2 diabetes mellitus in Chinese elderly
title_fullStr	Body mass index is associated with type 2 diabetes mellitus in Chinese elderly
title_full_unstemmed	Body mass index is associated with type 2 diabetes mellitus in Chinese elderly
title_sort	body mass index is associated with type 2 diabetes mellitus in chinese elderly
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/9271febabf4b4f07b3d9af9f65ddb641
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_version_	1718396545414463488

Body mass index is associated with type 2 diabetes mellitus in Chinese elderly

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