Changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK

Changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK

Mohamed Hosny,1 Rania M Zaki,1 Rania A Ahmed,1 Noha Khalil,1 Hoda M Mostafa1 1Department of Ophthalmology, Cairo University, Cairo, Egypt Purpose: To study the influence of the transient elevation of intraocular pressure during suction in laser-assisted in situ keratomileusis (LASIK) on the retinal...

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Autores principales: Hosny M, Zaki RM, Ahmed RA, Khalil N, Mostafa HM
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Publicado: Dove Medical Press 2013
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Ophthalmology
RE1-994
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spelling oai:doaj.org-article:9279354865ef4d3da17e767edfd220222021-12-02T05:21:05ZChanges in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK1177-54671177-5483https://doaj.org/article/9279354865ef4d3da17e767edfd220222013-09-01T00:00:00Zhttp://www.dovepress.com/changes-in-retinal-nerve-fiber-layer-thickness-following-mechanical-mi-a14474https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Mohamed Hosny,1 Rania M Zaki,1 Rania A Ahmed,1 Noha Khalil,1 Hoda M Mostafa1 1Department of Ophthalmology, Cairo University, Cairo, Egypt Purpose: To study the influence of the transient elevation of intraocular pressure during suction in laser-assisted in situ keratomileusis (LASIK) on the retinal nerve fiber layer (RNFL) thickness both in microkeratome assisted and femotsecond (FS) LASIK. Patients and methods: An interventional case series that included 40 eyes suffering from myopia who were candidates for LASIK. All underwent Wave Front Guided LASIK by the same surgeon using the VisX CustomVue platform. A corneal flap was created in 20 eyes using a mechanical microkeratome Moria M2 (MMK), while the IFS IntraLase™ was used in the remaining 20 eyes. Mean suction time was recorded from “Suction ON” to “Suction OFF” time. Optic cube and RNFL thickness analysis using Spectral Domain Optical Coherence Tomography (SD-OCT) Cirrus-HD was completed before, and 1 month after LASIK. Results: The study included 40 eyes of 20 patients. All were females with mean age 33.5 ± 6.4 years. Mean preoperative spherical equivalent was −3.62 ± 2.31D. Average preoperative RNFL thickness was 94.6 ± 12.1µm in MMK group while the postoperative average thickness was 95.1 ± 11.9 um with no statistically significant difference (P-value: 0.37). Average preoperative RNFL thickness was 108.28 ± 8.4 µm in FS group compared to 108.38 ± 11.2 µm in the postoperative average with no statistically significant difference (P-value: 0.94). Mean “Suction ON” to “Suction OFF” time was 22 seconds in the MMK group compared to 41 seconds in the FS group. Conclusion: The rise of intraocular pressure during application of suction ring in LASIK surgery does not affect the RNFL thickness as measured by SD-OCT, whether the flap is created by MMK or FS. Keywords: intraocular pressure, laser-assisted in situ keratomileusis, retinal thicknessHosny MZaki RMAhmed RAKhalil NMostafa HMDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1919-1922 (2013)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Hosny M
Zaki RM
Ahmed RA
Khalil N
Mostafa HM
Changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK
description Mohamed Hosny,1 Rania M Zaki,1 Rania A Ahmed,1 Noha Khalil,1 Hoda M Mostafa1 1Department of Ophthalmology, Cairo University, Cairo, Egypt Purpose: To study the influence of the transient elevation of intraocular pressure during suction in laser-assisted in situ keratomileusis (LASIK) on the retinal nerve fiber layer (RNFL) thickness both in microkeratome assisted and femotsecond (FS) LASIK. Patients and methods: An interventional case series that included 40 eyes suffering from myopia who were candidates for LASIK. All underwent Wave Front Guided LASIK by the same surgeon using the VisX CustomVue platform. A corneal flap was created in 20 eyes using a mechanical microkeratome Moria M2 (MMK), while the IFS IntraLase™ was used in the remaining 20 eyes. Mean suction time was recorded from “Suction ON” to “Suction OFF” time. Optic cube and RNFL thickness analysis using Spectral Domain Optical Coherence Tomography (SD-OCT) Cirrus-HD was completed before, and 1 month after LASIK. Results: The study included 40 eyes of 20 patients. All were females with mean age 33.5 ± 6.4 years. Mean preoperative spherical equivalent was −3.62 ± 2.31D. Average preoperative RNFL thickness was 94.6 ± 12.1µm in MMK group while the postoperative average thickness was 95.1 ± 11.9 um with no statistically significant difference (P-value: 0.37). Average preoperative RNFL thickness was 108.28 ± 8.4 µm in FS group compared to 108.38 ± 11.2 µm in the postoperative average with no statistically significant difference (P-value: 0.94). Mean “Suction ON” to “Suction OFF” time was 22 seconds in the MMK group compared to 41 seconds in the FS group. Conclusion: The rise of intraocular pressure during application of suction ring in LASIK surgery does not affect the RNFL thickness as measured by SD-OCT, whether the flap is created by MMK or FS. Keywords: intraocular pressure, laser-assisted in situ keratomileusis, retinal thickness
format article
author Hosny M
Zaki RM
Ahmed RA
Khalil N
Mostafa HM
author_facet Hosny M
Zaki RM
Ahmed RA
Khalil N
Mostafa HM
author_sort Hosny M
title Changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK
title_short Changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK
title_full Changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK
title_fullStr Changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK
title_full_unstemmed Changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK
title_sort changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted lasik
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/9279354865ef4d3da17e767edfd22022
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AT ahmedra changesinretinalnervefiberlayerthicknessfollowingmechanicalmicrokeratomeassistedversusfemtosecondlaserassistedlasik
AT khaliln changesinretinalnervefiberlayerthicknessfollowingmechanicalmicrokeratomeassistedversusfemtosecondlaserassistedlasik
AT mostafahm changesinretinalnervefiberlayerthicknessfollowingmechanicalmicrokeratomeassistedversusfemtosecondlaserassistedlasik
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