Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation.

Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation.

<h4>Background</h4>Demyelination and axonal damage are critical processes in the pathogenesis of multiple sclerosis (MS). Oxidative stress and pro-inflammatory cytokines elicited by inflammation mediates tissue damage.<h4>Methods/principal findings</h4>To monitor the demyelin...

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Autores principales: Alessandra di Penta, Beatriz Moreno, Stephanie Reix, Begoña Fernandez-Diez, Maite Villanueva, Oihana Errea, Nagore Escala, Koen Vandenbroeck, Joan X Comella, Pablo Villoslada
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/927b9a4c1ce74559acbcc044cb2ad8a1
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