A redox-neutral catechol synthesis
Catechols are common structural motifs in bioactive molecules and synthetic building blocks. Here the authors report a method to convert phenol derivatives into catechols via an iridium-catalysed redox-neutral C–H hydroxylation, giving diversely substituted products under mild conditions.
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Nature Portfolio
2017
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oai:doaj.org-article:928132b5484e4544bc685b1aa58106ca2021-12-02T14:42:05ZA redox-neutral catechol synthesis10.1038/ncomms142272041-1723https://doaj.org/article/928132b5484e4544bc685b1aa58106ca2017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14227https://doaj.org/toc/2041-1723Catechols are common structural motifs in bioactive molecules and synthetic building blocks. Here the authors report a method to convert phenol derivatives into catechols via an iridium-catalysed redox-neutral C–H hydroxylation, giving diversely substituted products under mild conditions.Qian WuDingyuan YanYing ChenTing WangFeng XiongWei WeiYi LuWei-Yin SunJie Jack LiJing ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Qian Wu Dingyuan Yan Ying Chen Ting Wang Feng Xiong Wei Wei Yi Lu Wei-Yin Sun Jie Jack Li Jing Zhao A redox-neutral catechol synthesis |
description |
Catechols are common structural motifs in bioactive molecules and synthetic building blocks. Here the authors report a method to convert phenol derivatives into catechols via an iridium-catalysed redox-neutral C–H hydroxylation, giving diversely substituted products under mild conditions. |
format |
article |
author |
Qian Wu Dingyuan Yan Ying Chen Ting Wang Feng Xiong Wei Wei Yi Lu Wei-Yin Sun Jie Jack Li Jing Zhao |
author_facet |
Qian Wu Dingyuan Yan Ying Chen Ting Wang Feng Xiong Wei Wei Yi Lu Wei-Yin Sun Jie Jack Li Jing Zhao |
author_sort |
Qian Wu |
title |
A redox-neutral catechol synthesis |
title_short |
A redox-neutral catechol synthesis |
title_full |
A redox-neutral catechol synthesis |
title_fullStr |
A redox-neutral catechol synthesis |
title_full_unstemmed |
A redox-neutral catechol synthesis |
title_sort |
redox-neutral catechol synthesis |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/928132b5484e4544bc685b1aa58106ca |
work_keys_str_mv |
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1718389823088099328 |