Smoking Cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation

Abstract Background Smokers present a higher prevalence and severity of periodontitis and, consequently, higher prevalence of tooth loss. Smoking cessation improves the response to periodontal treatment and reduces tooth loss. So, the aim of this study was to evaluate the efficiency in resources all...

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Autores principales:	Maria Luisa Silveira Souto, Fernanda Campos de Almeida Carrer, Mariana Minatel Braga, Cláudio Mendes Pannuti
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Cigarette smoking Smoking cessation Periodontitis Health economics Modelling Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/9287de786948468a947cbc295f47560b
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spelling	oai:doaj.org-article:9287de786948468a947cbc295f47560b2021-12-05T12:20:35ZSmoking Cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation10.1186/s12903-021-01932-21472-6831https://doaj.org/article/9287de786948468a947cbc295f47560b2021-12-01T00:00:00Zhttps://doi.org/10.1186/s12903-021-01932-2https://doaj.org/toc/1472-6831Abstract Background Smokers present a higher prevalence and severity of periodontitis and, consequently, higher prevalence of tooth loss. Smoking cessation improves the response to periodontal treatment and reduces tooth loss. So, the aim of this study was to evaluate the efficiency in resources allocation when implementing smoking cessation therapy vs. its non-implementation in smokers with periodontitis. Methods We adopted the Brazilian public system perspective to determine the incremental cost-effectiveness (cost per tooth loss avoided) and cost-utility (cost per oral-related quality-adjusted life-year ([QALY] gained) of implementing smoking cessation therapy. Base-case was defined as a 48 years-old male subject and horizon of 30 years. Effects and costs were combined in a decision analytic modeling framework to permit a quantitative approach aiming to estimate the value of the consequences of smoking cessation therapy adjusted for their probability of occurrence. Markov models were carried over annual cycles. Sensitivity analysis tested methodological assumptions. Results Implementing the therapy saved approximately US$ 100 over the time horizon accompanied by a slightly better effect, both in CEA and CUA. Considering uncertainties, the therapy could be cost-effective in the most part of simulated cases, even being cheaper and more effective in 35% of cases in which the oral-health related outcome is used as effect. Considering a willingness-to-pay of US$100 per health effect, smoking cessation therapy was cost-effective, respectively, in 72% and 99% of cases in cost-utility and cost-effectiveness analyses. Conclusions Implementation of smoking cessation therapy may be cost-effective, considering the avoidance of tooth loss and oral health-related consequences to patients.Maria Luisa Silveira SoutoFernanda Campos de Almeida CarrerMariana Minatel BragaCláudio Mendes PannutiBMCarticleCigarette smokingSmoking cessationPeriodontitisHealth economicsModellingDentistryRK1-715ENBMC Oral Health, Vol 21, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cigarette smoking Smoking cessation Periodontitis Health economics Modelling Dentistry RK1-715
spellingShingle	Cigarette smoking Smoking cessation Periodontitis Health economics Modelling Dentistry RK1-715 Maria Luisa Silveira Souto Fernanda Campos de Almeida Carrer Mariana Minatel Braga Cláudio Mendes Pannuti Smoking Cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation
description	Abstract Background Smokers present a higher prevalence and severity of periodontitis and, consequently, higher prevalence of tooth loss. Smoking cessation improves the response to periodontal treatment and reduces tooth loss. So, the aim of this study was to evaluate the efficiency in resources allocation when implementing smoking cessation therapy vs. its non-implementation in smokers with periodontitis. Methods We adopted the Brazilian public system perspective to determine the incremental cost-effectiveness (cost per tooth loss avoided) and cost-utility (cost per oral-related quality-adjusted life-year ([QALY] gained) of implementing smoking cessation therapy. Base-case was defined as a 48 years-old male subject and horizon of 30 years. Effects and costs were combined in a decision analytic modeling framework to permit a quantitative approach aiming to estimate the value of the consequences of smoking cessation therapy adjusted for their probability of occurrence. Markov models were carried over annual cycles. Sensitivity analysis tested methodological assumptions. Results Implementing the therapy saved approximately US$ 100 over the time horizon accompanied by a slightly better effect, both in CEA and CUA. Considering uncertainties, the therapy could be cost-effective in the most part of simulated cases, even being cheaper and more effective in 35% of cases in which the oral-health related outcome is used as effect. Considering a willingness-to-pay of US$100 per health effect, smoking cessation therapy was cost-effective, respectively, in 72% and 99% of cases in cost-utility and cost-effectiveness analyses. Conclusions Implementation of smoking cessation therapy may be cost-effective, considering the avoidance of tooth loss and oral health-related consequences to patients.
format	article
author	Maria Luisa Silveira Souto Fernanda Campos de Almeida Carrer Mariana Minatel Braga Cláudio Mendes Pannuti
author_facet	Maria Luisa Silveira Souto Fernanda Campos de Almeida Carrer Mariana Minatel Braga Cláudio Mendes Pannuti
author_sort	Maria Luisa Silveira Souto
title	Smoking Cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation
title_short	Smoking Cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation
title_full	Smoking Cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation
title_fullStr	Smoking Cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation
title_full_unstemmed	Smoking Cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation
title_sort	smoking cessation therapy is a cost-effective intervention to avoid tooth loss in brazilian subjects with periodontitis: an economic evaluation
publisher	BMC
publishDate	2021
url	https://doaj.org/article/9287de786948468a947cbc295f47560b
work_keys_str_mv	AT marialuisasilveirasouto smokingcessationtherapyisacosteffectiveinterventiontoavoidtoothlossinbraziliansubjectswithperiodontitisaneconomicevaluation AT fernandacamposdealmeidacarrer smokingcessationtherapyisacosteffectiveinterventiontoavoidtoothlossinbraziliansubjectswithperiodontitisaneconomicevaluation AT marianaminatelbraga smokingcessationtherapyisacosteffectiveinterventiontoavoidtoothlossinbraziliansubjectswithperiodontitisaneconomicevaluation AT claudiomendespannuti smokingcessationtherapyisacosteffectiveinterventiontoavoidtoothlossinbraziliansubjectswithperiodontitisaneconomicevaluation
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Smoking Cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation

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