Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine

Anna I Guerdjikova,1,2 Nicole Mori,1,2 Leah S Casuto,1,2 Susan L McElroy1,2 1Lindner Center of HOPE, Mason, OH, USA; 2Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA Abstract: Binge eating disorder (BED) is the most common eat...

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Autores principales: Guerdjikova AI, Mori N, Casuto LS, McElroy SL
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2016
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Acceso en línea:https://doaj.org/article/928e8fc953654f57973a941040c786e4
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spelling oai:doaj.org-article:928e8fc953654f57973a941040c786e42021-12-02T02:55:33ZNovel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine1178-2021https://doaj.org/article/928e8fc953654f57973a941040c786e42016-04-01T00:00:00Zhttps://www.dovepress.com/novel-pharmacologic-treatment-in-acute-binge-eating-disorder-ndash-rol-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Anna I Guerdjikova,1,2 Nicole Mori,1,2 Leah S Casuto,1,2 Susan L McElroy1,2 1Lindner Center of HOPE, Mason, OH, USA; 2Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA Abstract: Binge eating disorder (BED) is the most common eating disorder and an important public health problem. It is characterized by recurrent episodes of excessive food consumption accompanied by a sense of loss of control over the binge eating behavior without the inappropriate compensatory weight loss behaviors of bulimia nervosa. BED affects both sexes and all age groups and is associated with medical and psychiatric comorbidities. Until recently, self-help and psychotherapy were the primary treatment options for patients with BED. In early 2015, lisdexamfetamine dimesylate, a prodrug stimulant marketed for attention deficit hyperactive disorder, was the first pharmacologic agent to be approved by the US Food and Drug Administration for the treatment of moderate or severe BED in adults. This article summarizes BED clinical presentation, and discusses the pharmacokinetic profile, efficacy, and safety of lisdexamfetamine dimesylate in the treatment of BED in adults. Keywords: binging, overeating, Vyvanse, stimulant, approved medicationGuerdjikova AIMori NCasuto LSMcElroy SLDove Medical PressarticleKey words: binge eatinglisdexamfetamine dimesylatestimulantsovereatingNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2016, Iss Issue 1, Pp 833-841 (2016)
institution DOAJ
collection DOAJ
language EN
topic Key words: binge eating
lisdexamfetamine dimesylate
stimulants
overeating
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Key words: binge eating
lisdexamfetamine dimesylate
stimulants
overeating
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Guerdjikova AI
Mori N
Casuto LS
McElroy SL
Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
description Anna I Guerdjikova,1,2 Nicole Mori,1,2 Leah S Casuto,1,2 Susan L McElroy1,2 1Lindner Center of HOPE, Mason, OH, USA; 2Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA Abstract: Binge eating disorder (BED) is the most common eating disorder and an important public health problem. It is characterized by recurrent episodes of excessive food consumption accompanied by a sense of loss of control over the binge eating behavior without the inappropriate compensatory weight loss behaviors of bulimia nervosa. BED affects both sexes and all age groups and is associated with medical and psychiatric comorbidities. Until recently, self-help and psychotherapy were the primary treatment options for patients with BED. In early 2015, lisdexamfetamine dimesylate, a prodrug stimulant marketed for attention deficit hyperactive disorder, was the first pharmacologic agent to be approved by the US Food and Drug Administration for the treatment of moderate or severe BED in adults. This article summarizes BED clinical presentation, and discusses the pharmacokinetic profile, efficacy, and safety of lisdexamfetamine dimesylate in the treatment of BED in adults. Keywords: binging, overeating, Vyvanse, stimulant, approved medication
format article
author Guerdjikova AI
Mori N
Casuto LS
McElroy SL
author_facet Guerdjikova AI
Mori N
Casuto LS
McElroy SL
author_sort Guerdjikova AI
title Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_short Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_full Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_fullStr Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_full_unstemmed Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_sort novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/928e8fc953654f57973a941040c786e4
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AT morin novelpharmacologictreatmentinacutebingeeatingdisorderndashroleoflisdexamfetamine
AT casutols novelpharmacologictreatmentinacutebingeeatingdisorderndashroleoflisdexamfetamine
AT mcelroysl novelpharmacologictreatmentinacutebingeeatingdisorderndashroleoflisdexamfetamine
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