Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia

Background: The most common cause of hospital admission in the first month of life is the neonatal jaundice. Some factors [e.g., prenatal, neonatal factors, maternal factors, and environmental factors (such as zinc) influence the frequency of neonatal jaundice. In terms of neonates, it is proposed t...

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Autores principales: Saeda Ali, Mohamed Abdel-aal, Mohamed Elsamanoudy, Sabah Ibrahim
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Lenguaje:EN
Publicado: Al-Azhar University, Faculty of Medicine (Damietta) 2020
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Acceso en línea:https://doaj.org/article/928f81beaae7458c89bae9e97b5d2807
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spelling oai:doaj.org-article:928f81beaae7458c89bae9e97b5d28072021-12-02T14:02:00ZSerum Zinc Level in Neonates with Indirect Hyperbilirubinemia2636-41742682-378010.21608/ijma.2019.18377.1038https://doaj.org/article/928f81beaae7458c89bae9e97b5d28072020-01-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_65788_cc5f68a0d8d7e663ba7ad2debd8fb752.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: The most common cause of hospital admission in the first month of life is the neonatal jaundice. Some factors [e.g., prenatal, neonatal factors, maternal factors, and environmental factors (such as zinc) influence the frequency of neonatal jaundice. In terms of neonates, it is proposed that there is a correlation between serum zinc quality and hyperbilirubinemia. Aim of the work: To evaluate the level of serum zinc in term neonates with indirect hyperbilirubinemia. Patients and Methods: A case control study carried out at the neonatal intensive care unit (NICU) and pediatric outpatient clinic of New Damietta, Al-Azhar University Hospital, from June 2018 to February 2019. It included 75 neonates with neonatal jaundice as cases group and 75 healthy neonates of matched age and sex as a control group. All were assessed clinically and serum zinc levels were determined and documented. Results: Level of serum zinc in neonates with non-hemolytic hyperbilirubinemia (103.3±36.56 ug/dl) was significantly lower than healthy neonates without jaundice (128.62 ± 40.83 ug/dl) and zinc deficiency in jaundiced neonates (25.3%) was statistically significant more than healthy neonates) 6.7%). There was no significant relation between the level of serum zinc and other factors like the maternal age, parity, pattern of feeding, gender and weight, but there was significant correlation with maternal zinc intake during pregnancy. Conclusion: We concluded that serum zinc level in term neonates with neonatal jaundice was statistically significant decreased than healthy term neonates.Saeda AliMohamed Abdel-aalMohamed ElsamanoudySabah IbrahimAl-Azhar University, Faculty of Medicine (Damietta)articlezincindirecthemolytichyperbilirubinemianeonatesMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 1, Pp 217-222 (2020)
institution DOAJ
collection DOAJ
language EN
topic zinc
indirect
hemolytic
hyperbilirubinemia
neonates
Medicine (General)
R5-920
spellingShingle zinc
indirect
hemolytic
hyperbilirubinemia
neonates
Medicine (General)
R5-920
Saeda Ali
Mohamed Abdel-aal
Mohamed Elsamanoudy
Sabah Ibrahim
Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia
description Background: The most common cause of hospital admission in the first month of life is the neonatal jaundice. Some factors [e.g., prenatal, neonatal factors, maternal factors, and environmental factors (such as zinc) influence the frequency of neonatal jaundice. In terms of neonates, it is proposed that there is a correlation between serum zinc quality and hyperbilirubinemia. Aim of the work: To evaluate the level of serum zinc in term neonates with indirect hyperbilirubinemia. Patients and Methods: A case control study carried out at the neonatal intensive care unit (NICU) and pediatric outpatient clinic of New Damietta, Al-Azhar University Hospital, from June 2018 to February 2019. It included 75 neonates with neonatal jaundice as cases group and 75 healthy neonates of matched age and sex as a control group. All were assessed clinically and serum zinc levels were determined and documented. Results: Level of serum zinc in neonates with non-hemolytic hyperbilirubinemia (103.3±36.56 ug/dl) was significantly lower than healthy neonates without jaundice (128.62 ± 40.83 ug/dl) and zinc deficiency in jaundiced neonates (25.3%) was statistically significant more than healthy neonates) 6.7%). There was no significant relation between the level of serum zinc and other factors like the maternal age, parity, pattern of feeding, gender and weight, but there was significant correlation with maternal zinc intake during pregnancy. Conclusion: We concluded that serum zinc level in term neonates with neonatal jaundice was statistically significant decreased than healthy term neonates.
format article
author Saeda Ali
Mohamed Abdel-aal
Mohamed Elsamanoudy
Sabah Ibrahim
author_facet Saeda Ali
Mohamed Abdel-aal
Mohamed Elsamanoudy
Sabah Ibrahim
author_sort Saeda Ali
title Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia
title_short Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia
title_full Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia
title_fullStr Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia
title_full_unstemmed Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia
title_sort serum zinc level in neonates with indirect hyperbilirubinemia
publisher Al-Azhar University, Faculty of Medicine (Damietta)
publishDate 2020
url https://doaj.org/article/928f81beaae7458c89bae9e97b5d2807
work_keys_str_mv AT saedaali serumzinclevelinneonateswithindirecthyperbilirubinemia
AT mohamedabdelaal serumzinclevelinneonateswithindirecthyperbilirubinemia
AT mohamedelsamanoudy serumzinclevelinneonateswithindirecthyperbilirubinemia
AT sabahibrahim serumzinclevelinneonateswithindirecthyperbilirubinemia
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