Replication-dependent size reduction precedes differentiation in Chlamydia trachomatis

The vegetative forms of chlamydiae (RBs) replicate within infected cells and then convert into infectious forms (EBs). Here, the authors use quantitative 3D electron microscopy and computer modeling to show that RB size decreases with replication, and conversion into EBs correlates with an RB size t...

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Auteurs principaux:	Jennifer K. Lee, Germán A. Enciso, Daniela Boassa, Christopher N. Chander, Tracy H. Lou, Sean S. Pairawan, Melody C. Guo, Frederic Y. M. Wan, Mark H. Ellisman, Christine Sütterlin, Ming Tan
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/9291b912725f480abdf2623db34a8d20
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spelling	oai:doaj.org-article:9291b912725f480abdf2623db34a8d202021-12-02T14:40:43ZReplication-dependent size reduction precedes differentiation in Chlamydia trachomatis10.1038/s41467-017-02432-02041-1723https://doaj.org/article/9291b912725f480abdf2623db34a8d202018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02432-0https://doaj.org/toc/2041-1723The vegetative forms of chlamydiae (RBs) replicate within infected cells and then convert into infectious forms (EBs). Here, the authors use quantitative 3D electron microscopy and computer modeling to show that RB size decreases with replication, and conversion into EBs correlates with an RB size threshold.Jennifer K. LeeGermán A. EncisoDaniela BoassaChristopher N. ChanderTracy H. LouSean S. PairawanMelody C. GuoFrederic Y. M. WanMark H. EllismanChristine SütterlinMing TanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jennifer K. Lee Germán A. Enciso Daniela Boassa Christopher N. Chander Tracy H. Lou Sean S. Pairawan Melody C. Guo Frederic Y. M. Wan Mark H. Ellisman Christine Sütterlin Ming Tan Replication-dependent size reduction precedes differentiation in Chlamydia trachomatis
description	The vegetative forms of chlamydiae (RBs) replicate within infected cells and then convert into infectious forms (EBs). Here, the authors use quantitative 3D electron microscopy and computer modeling to show that RB size decreases with replication, and conversion into EBs correlates with an RB size threshold.
format	article
author	Jennifer K. Lee Germán A. Enciso Daniela Boassa Christopher N. Chander Tracy H. Lou Sean S. Pairawan Melody C. Guo Frederic Y. M. Wan Mark H. Ellisman Christine Sütterlin Ming Tan
author_facet	Jennifer K. Lee Germán A. Enciso Daniela Boassa Christopher N. Chander Tracy H. Lou Sean S. Pairawan Melody C. Guo Frederic Y. M. Wan Mark H. Ellisman Christine Sütterlin Ming Tan
author_sort	Jennifer K. Lee
title	Replication-dependent size reduction precedes differentiation in Chlamydia trachomatis
title_short	Replication-dependent size reduction precedes differentiation in Chlamydia trachomatis
title_full	Replication-dependent size reduction precedes differentiation in Chlamydia trachomatis
title_fullStr	Replication-dependent size reduction precedes differentiation in Chlamydia trachomatis
title_full_unstemmed	Replication-dependent size reduction precedes differentiation in Chlamydia trachomatis
title_sort	replication-dependent size reduction precedes differentiation in chlamydia trachomatis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/9291b912725f480abdf2623db34a8d20
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Replication-dependent size reduction precedes differentiation in Chlamydia trachomatis

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